2,3-Diphenylindolizine

Base Information

• Chemical Name: 2,3-Diphenylindolizine
• CAS No.: 21812-61-3
• Molecular Formula: C20H15 N
• Molecular Weight: 269.346
• Hs Code.: 2933990090
• European Community (EC) Number: 244-592-0
• UNII: VG4N58CX7V
• DSSTox Substance ID: DTXSID1066734
• Nikkaji Number: J225.443C
• Wikidata: Q81993316
• Mol file: 21812-61-3.mol

Synonyms:2,3-Diphenylindolizine;Indolizine, 2,3-diphenyl-;21812-61-3;EINECS 244-592-0;VG4N58CX7V;SCHEMBL9187424;DTXSID1066734

Chemical Property of 2,3-Diphenylindolizine

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 4.41000
• Density: 1.07g/cm³
• LogP: 5.27330
• XLogP3: 5.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 269.120449483
• Heavy Atom Count: 21
• Complexity: 327

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=C(N3C=CC=CC3=C2)C4=CC=CC=C4

Technology Process of 2,3-Diphenylindolizine

There total 3 articles about 2,3-Diphenylindolizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-phenylindolizine (25379-20-8) + iodobenzene (591-50-4) → 2,3-diphenyl-indolizine (21812-61-3)

Guidance literature:

With anhydrous potassium acetate; In N,N-dimethyl acetamide; at 150 ℃; for 24h; Sealed tube;

DOI:10.1039/d1dt02985a

Reference yield: 85.0%

bromobenzene (108-86-1,52753-63-6) + 2-phenylindolizine (25379-20-8) → 2,3-diphenyl-indolizine (21812-61-3)

Guidance literature:

With anhydrous potassium acetate; In N,N-dimethyl acetamide; at 150 ℃; for 24h; Sealed tube;

DOI:10.1039/d1dt02985a

Reference yield:

→ 2,3-diphenyl-indolizine (21812-61-3)

Guidance literature:

2,3-Diphenyl-1-carboxyindolizin, >198grad;

DOI:10.1039/jr9620002627

upstream raw materials:

bromobenzene

2-phenylindolizine

iodobenzene

Downstream raw materials:

1,3-bis-(2,3-diphenyl-indolizin-1-yl)-trimethinium ; bromide

Refernces