Adenine hydrochloride

Base Information

• Chemical Name: Adenine hydrochloride
• CAS No.: 2922-28-3
• Molecular Formula: C5H5N5^.HCl
• Molecular Weight: 171.589
• Hs Code.: 29335990
• European Community (EC) Number: 220-867-0,244-817-2
• UNII: 364H11M7OD
• DSSTox Substance ID: DTXSID10883907
• Wikidata: Q27256522
• ChEMBL ID: CHEMBL539503
• Mol file: 2922-28-3.mol

Synonyms:Adenine hydrochloride;2922-28-3;6-Aminopurine hydrochloride;7H-purin-6-amine hydrochloride;ADENINE HCL;Adenine monohydrochloride;1H-Purin-6-amine, monohydrochloride;9H-Purin-6-amine, hydrochloride (1:1);Adenine (hydrochloride);22177-51-1;1H-Purin-6-amine, hydrochloride;1H-Adenine hydrochloride;UNII-364H11M7OD;CHEMBL539503;9H-purin-6-amine hydrochloride;364H11M7OD;EINECS 220-867-0;EINECS 244-817-2;9H-Purin-6-amine, hydrochloride (1:?);6-Aminopurine (hydrochloride);Vitamin B4 (hydrochloride);Adeninehydrochloride;1h-purin-6-amine monohydrochloride;C5H5N5.xClH;adenine hydrochloride salt;Adenine, monohydrochloride;C5H5N5.ClH;C5-H5-N5.x-Cl-H;MLS001333591;SCHEMBL680904;C5-H5-N5.Cl-H;7H-purin-6-amine;hydrochloride;HY-B0152A;TIMTEC-BB SBB003841;DTXSID10883907;BCPP000432;BCP02866;BDBM50228485;MFCD00038990;MFCD00075782;s1983;ADENINE HYDROCHLORIDE [WHO-DD];AKOS015894551;AKOS015961102;AKOS016010514;AM83909;BCP9000234;CCG-266366;AC-12914;AS-12076;SMR000875287;A0150;CS-0013153;FT-0621900;SW219881-1;Adenine monohydrochloride, >=99.0% (HPLC);D77992;Adenine hydrochloride, cont. up to ca 5% water;EN300-7379677;A819823;J-519541;Q-200596;Q27256522

Chemical Property of Adenine hydrochloride

Chemical Property:

• Appearance/Colour: white to light yellow crystal powder
• Melting Point: ~285 °C (dec.)
• Boiling Point: 553.5 °C at 760 mmHg
• Flash Point: 322.7 °C
• PSA: 80.48000
• LogP: 1.31830
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: H2O: 50 mg/mL
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 171.0311729
• Heavy Atom Count: 11
• Complexity: 127

Purity/Quality:

99% ^*data from raw suppliers

Adenine HCl ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38
• Safety Statements: 26-36-36/37/39-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Biological Agents -> Nucleic Acids and Derivatives
• Canonical SMILES: C1=NC2=NC=NC(=C2N1)N.Cl
• Uses: Adenine hydrochloride hydrate has been used:As a component of FAD cell culture mediaIn maintaining organotypic cultures for recreating stratified epithelium from primary cell culturesIn limbal-corneal epithelial culturing and keratinocytes Adenine is a purine nucleobase with a wide range of chemical and biochemical roles in vivo and in vitro. It is a regulatory molecule and a component of DNA, RNA, cofactors (NAD, FAD) and signaling molecules (cAMP).

Technology Process of Adenine hydrochloride

There total 2 articles about Adenine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1,2,3,4-tetrahydronaphthalen-1-amine (2217-40-5) + 6-chloropurine (87-42-3) → adenine hydrochloride (2922-28-3)

Guidance literature:

In isopropyl alcohol;

Reference yield:

adenine (66224-66-6,66224-67-7,66224-68-8,66224-69-9,134434-48-3,134434-49-4,134454-76-5,134461-75-9) → adenine hydrochloride (2922-28-3)

Guidance literature:

With hydrogenchloride; In water;

DOI:10.1039/b606249k

upstream raw materials:

adenine

1,2,3,4-tetrahydronaphthalen-1-amine

6-chloropurine

Refernces

• 1、 -. "Aryl and heteroaryl purine compounds". . . Retrieved 2008/06/13.