2,3,5,6-Tetraphenylpyrazine

Base Information Edit

Chemical Name:2,3,5,6-Tetraphenylpyrazine
CAS No.:642-04-6
Molecular Formula:C28H20 N2
Molecular Weight:384.48
Hs Code.:2933990090
European Community (EC) Number:636-338-6
NSC Number:123074
UNII:PPA8GH77SZ
DSSTox Substance ID:DTXSID70298432
Nikkaji Number:J7.056D
Wikidata:Q82040241
ChEMBL ID:CHEMBL11842
Mol file:642-04-6.mol

Synonyms:amaron;2,3,5,6-tetraphenylpyrazine;642-04-6;tetraphenylpyrazine;pyrazine, 2,3,5,6-tetraphenyl-;NSC-123074;Pyrazine, tetraphenyl-;amarone;2,3,5,6-Tetraphenyl-pyrazine;NSC123074;PPA8GH77SZ;SCHEMBL65673;CHEMBL11842;DTXSID70298432;AMY31974;AKOS000279772;UPCMLD0ENAT5337378:001;NCGC00340817-01;2,3,5,6-tetraphenylpyrazine (alpha form);2,3,5,6-TETRAPHENYLPYRAZINE (AMARON);F74957;AB01106365-03;Z85930640

Suppliers and Price of 2,3,5,6-Tetraphenylpyrazine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 11 raw suppliers

Chemical Property of 2,3,5,6-Tetraphenylpyrazine Edit

Chemical Property:

Vapor Pressure:2.75E-09mmHg at 25°C
Melting Point:246-247 °C
Boiling Point:490.4°Cat760mmHg
PKA:-0.90±0.10(Predicted)
Flash Point:187.1°C
PSA：25.78000
Density:1.14g/cm³
LogP:7.14460
Storage Temp.:Refrigerator, under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:6.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:384.162648646
Heavy Atom Count:30
Complexity:405

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(N=C(C(=N2)C3=CC=CC=C3)C4=CC=CC=C4)C5=CC=CC=C5
Uses 2,3,5,6-Tetraphenylpyrazine exhibits antidiabetic activity in sucrose-loaded and streptozotocin-induced diabetic rat models.

Technology Process of 2,3,5,6-Tetraphenylpyrazine

There total 135 articles about 2,3,5,6-Tetraphenylpyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 119-53-9,579-44-2
2-hydroxy-2-phenylacetophenone

: 100-52-7
benzaldehyde

: 484-47-9
lophine

: 642-04-6
2,3,5,6-tetraphenylpyrazine

Guidance literature:: With cerium(III) chloride heptahydrate; ammonium acetate; In ethanol; for 4h; Reflux;
DOI:10.1590/S0103-50532012000100024

Reference yield: 42.0%

: 109-99-9,24979-97-3,77392-70-2
tetrahydrofuran

: neodymium(II) diiodide

: 7732-18-5
water

: 100-47-0
benzonitrile

: 113316-94-2
tris(tetrahydrofurane)triiodidoneodymium(III)

: NdI(OH)2(H₂O)5

: 484-47-9
lophine

: 493-77-6
2,4,6-triphenyl-1,3,5-triazine

: 642-04-6
2,3,5,6-tetraphenylpyrazine

Guidance literature:: In tetrahydrofuran; conventional Schlenk technique; PhCN added with stirring to NdI2; 5 min;PhCN removed in vac.; THF added; pptd. for 1 h; decanted; solvent remov ed from mother liquor; MeOH added; pptd. (20°C, 20 h); MeOH removed from soln.; pptd. by adding H2O; ppt. after decantation washed with cold THF, dried in vac. (NdI3(thf)3);ppt. after H2O addition sepd. by centrifuging, dried (NdI(OH)2(H2O)5); elem. anal.;
DOI:10.1023/B:RUCB.0000037850.09936.95