3-Chloro-2-methylpropanoyl chloride

Base Information

• Chemical Name: 3-Chloro-2-methylpropanoyl chloride
• CAS No.: 7623-10-1
• Molecular Formula: C4H6Cl2O
• Molecular Weight: 140.997
• DSSTox Substance ID: DTXSID20497317
• Mol file: 7623-10-1.mol

Synonyms:3-chloro-2-methylpropanoyl chloride;7623-10-1;beta-chloroisobutyrylchloride;SCHEMBL1862378;3-chloro isobutyric acid chloride;DTXSID20497317;REBZXOIBOIJEAU-UHFFFAOYSA-N;3-chloro-2-methylpropionyl chloride;3-chloro-2-methyl-propionyl chloride;FT-0692105

Chemical Property of 3-Chloro-2-methylpropanoyl chloride

Chemical Property:

• Melting Point: -90°C
• Refractive Index: 1.4079 (estimate)
• Boiling Point: 189.51°C (rough estimate)
• PSA: 17.07000
• Density: 1.0174
• LogP: 1.62670
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 139.9795702
• Heavy Atom Count: 7
• Complexity: 72.1

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CCl)C(=O)Cl

Technology Process of 3-Chloro-2-methylpropanoyl chloride

There total 9 articles about 3-Chloro-2-methylpropanoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isobutyryl chloride (79-30-1) → 2-chloroisobutyryl chloride (13222-26-9) + 2-methyl-3-chloropropionyl chloride (7623-10-1,80141-51-1)

Guidance literature:

Photochlorierung in der Gasphase;

Reference yield:

tetrachloromethane (56-23-5) + sulfuryl dichloride (7791-25-5) + isobutyryl chloride (79-30-1) + dibenzoyl peroxide (94-36-0) → 2-chloroisobutyryl chloride (13222-26-9) + 2-methyl-3-chloropropionyl chloride (7623-10-1,80141-51-1)

Guidance literature:

im Dunkeln;

Reference yield:

chlorine (7782-50-5) + isobutyryl chloride (79-30-1) → 2-chloroisobutyryl chloride (13222-26-9) + 2-methyl-3-chloropropionyl chloride (7623-10-1,80141-51-1)

Guidance literature:

Photochlorierung in der Gasphase;

upstream raw materials:

isobutyryl chloride

(R)-(+)-β-chloro-isobutyric acid

chlorine

tetrachloromethane

Downstream raw materials:

3-methyl-2,3-dihydro-isoxazolo[3,2-b]quinazolin-9-one

4'-fluoro-2-methyl-3-chloro-propiophenone

2-methyl-5,6-dihydrocyclopenta[f]-1H-indene

p-chlorophenyl β-chloroisobutyrate

Refernces

• 1、 Kobyakova,Kuz'Mina,Beshenova,Beloded. "Development of the conditions of synthesis of p-chlorophenyl methacrylate of the desired purity grade". experimental part. p. 123 - 127. Retrieved 2009/09/06.
• 2、 -. "1,3-Diaryl-2-pyrazoline derivatives". . . Retrieved 2008/06/13.