(1R)-endo-(+)-Fenchyl alcohol

Base Information

• Chemical Name: (1R)-endo-(+)-Fenchyl alcohol
• CAS No.: 2217-02-9
• Molecular Formula: C10H18 O
• Molecular Weight: 154.252
• Hs Code.: 29061900
• UNII: OW0KEP592N,32Y92U27DU
• DSSTox Substance ID: DTXSID6044307
• Nikkaji Number: J156.724A
• Wikidata: Q64224715
• Metabolomics Workbench ID: 130692
• ChEMBL ID: CHEMBL3188732
• Mol file: 2217-02-9.mol

Synonyms:1,3,3-trimethyl-2-norbornanol;endo-fenchol;fenchol;fenchol, ((endo)-(+-))-isomer;fenchol, ((exo)-(+-))-isomer;fenchol, (1R-endo)-isomer;fenchol, (1S-endo)-isomer;fenchol, (1S-exo)-isomer;fenchol, (endo)-isomer;fenchol, (exo)-isomer;fenchyl alcohol

Chemical Property of (1R)-endo-(+)-Fenchyl alcohol

Chemical Property:

• Vapor Pressure: 0.0693mmHg at 25°C
• Melting Point: 39-45 ºC
• Refractive Index: 1.4790 (estimate)
• Boiling Point: 201-202 °C(lit.)
• PKA: 15.38±0.60(Predicted)
• Flash Point: 165 ºF
• PSA: 20.23000
• Density: 0.992g/cm³
• LogP: 2.19350
• Storage Temp.: 2-8°C
• Solubility.: Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
• Water Solubility.: Insoluble in water.
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 154.135765193
• Heavy Atom Count: 11
• Complexity: 185

Purity/Quality:

99.9% ^*data from raw suppliers

D-Fenchol ^*data from reagent suppliers

Safty Information:

• Statements: 36/38
• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1(C2CCC(C2)(C1O)C)C
• Isomeric SMILES: C[C@@]12CC[C@@H](C1)C([C@@H]2O)(C)C
• Uses: Solvent, organic intermediate, odorant, flavoring. (1R)-endo-(+)-Fenchyl alcohol?can be extensively used in daily chemicals such as fair antiperspirant, textile softener and liquid detergent. It can also be esterified by different kinds of organic acids to expand its usage in flavors and fragrances.

Technology Process of (1R)-endo-(+)-Fenchyl alcohol

There total 40 articles about (1R)-endo-(+)-Fenchyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

fenchone (4695-62-9,126-21-6) → Fenchol (4695-62-9,470-08-6,512-13-0,1632-73-1,2217-02-9,14575-74-7,22627-95-8,36386-49-9,36386-50-2,64439-31-2)

Guidance literature:

With ethanol; sodium; dl-fenchyl alcohol;

Reference yield:

→ Fenchol (4695-62-9,470-08-6,512-13-0,1632-73-1,2217-02-9,14575-74-7,22627-95-8,36386-49-9,36386-50-2,64439-31-2)

Guidance literature:

With ethanol; sodium; Ld"-fenchyl alcohol;

Reference yield:

ethanedioic acid 1,2-bis(1,3,3-trimethylbicyclo[2.2.1]hept-2-yl)ester (124118-33-8) → Fenchol (4695-62-9,470-08-6,512-13-0,1632-73-1,2217-02-9,14575-74-7,22627-95-8,36386-49-9,36386-50-2,64439-31-2)

Guidance literature:

With potassium hydroxide; inactive fenchyl alcohol;

upstream raw materials:

1,3,3-trimethyl-2-norbornanone

fenchone

ethanedioic acid 1,2-bis(1,3,3-trimethylbicyclo[2.2.1]hept-2-yl)ester

(+)-α-pinene

Downstream raw materials:

fenchone

fenchyl salicylate

Cyclohexyl-carbamic acid 1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester

cyclofenchene

Refernces

• 1、 Calderini, Elia,Drienovská, Ivana,Myrtollari, Kamela,Pressnig, Michaela,Sieber, Volker,Schwab, Helmut,Hofer, Michael,Kourist, Robert. "Simple Plug-In Synthetic Step for the Synthesis of (?)-Camphor from Renewable Starting Materials". . p. 2951 - 2956. Retrieved 2021/06/18.
• 2、 Reinhardt, Nicole,Fischer, Juliane,Coppi, Ralph,Blum, Elke,Brandt, Wolfgang,Draeger, Birgit. "Substrate flexibility and reaction specificity of tropinone reductase-like short-chain dehydrogenases". . p. 37 - 49. Retrieved 2014/03/21.