2-Propen-1-ol, 3-(4-methylphenyl)-, acetate, (2E)-

Base Information

• Chemical Name: 2-Propen-1-ol, 3-(4-methylphenyl)-, acetate, (2E)-
• CAS No.: 77134-00-0
• Molecular Formula: C12H14O2
• Molecular Weight: 190.242
• Mol file: 77134-00-0.mol

Synonyms:

Chemical Property of 2-Propen-1-ol, 3-(4-methylphenyl)-, acetate, (2E)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Propen-1-ol, 3-(4-methylphenyl)-, acetate, (2E)-

There total 29 articles about 2-Propen-1-ol, 3-(4-methylphenyl)-, acetate, (2E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

p-methylcinnamyl alcohol (122058-30-4) + acetic anhydride (108-24-7) → (E)-4-methylcinnamyl acetate (77134-00-0)

Guidance literature:

With dmap; In diethyl ether; at 20 ℃; for 18h; Inert atmosphere;

DOI:10.1002/chem.201406290

Reference yield: 98.0%

Allyl acetate (591-87-7) + 4-tolyl iodide (624-31-7) → (E)-4-methylcinnamyl acetate (77134-00-0)

Guidance literature:

With air; palladium diacetate; silver carbonate; In benzene; stereoselective reaction; Reflux;

DOI:10.1002/anie.200800966

Reference yield: 97.0%

1-(4'-methylphenyl)-prop-2-enyl acetate (107909-13-7) → (E)-4-methylcinnamyl acetate (77134-00-0)

Guidance literature:

With dichloro bis(acetonitrile) palladium(II); In tetrahydrofuran; at 25 ℃; for 14h;

DOI:10.1016/0040-4020(95)00481-M

upstream raw materials:

1-(3-chloro-1-propenyl)-4-methylbenzene

1-methyl-4-(prop-1-enyl)benzene

(E)-1-methyl-4-(prop-1-enyl)benzene

acetic acid

Downstream raw materials:

dimethyl (E)-2-(3-(4-methylphenyl)allyl)malonate

Phenyl 1-(4-methylphenyl)propyl ketone

(E)-4,4′-(prop-1-ene-1,3-diyl)bis(methylbenzene)

1-methyl-4-[(1E)-3-phenylprop-1-en-1-yl]benzene

Refernces

• 1、 Fegyverneki, Dániel,Kolozsvári, Natália,Molnár, Dániel,Egyed, Orsolya,Holczbauer, Tamás,Soós, Tibor. "Size-Exclusion Borane-Catalyzed Domino 1,3-Allylic/Reductive Ireland–Claisen Rearrangements: Impact of the Electronic and Structural Parameters on the 1,3-Allylic Shift Aptitude". supporting information. p. 2179 - 2183. Retrieved 2019/01/04.
• 2、 Zhu, Yuxiang,Colomer, Ignacio,Donohoe, Timothy J.. "Hypervalent iodine initiated intramolecular alkene dimerisation: A stereodivergent entry to cyclobutanes". supporting information. p. 10316 - 10319. Retrieved 2019/09/03.