2-(2-Hydroxyethoxy)ethyl decanoate

Base Information

• Chemical Name: 2-(2-Hydroxyethoxy)ethyl decanoate
• CAS No.: 7735-31-1
• Molecular Formula: C14H28O4
• DSSTox Substance ID: DTXSID90497546
• Wikidata: Q82347166
• Mol file: 7735-31-1.mol

Synonyms:7735-31-1;PEG2 Monodecanoate;2-(2-HYDROXYETHOXY)ETHYL DECANOATE;diethylene glycol monodecanoate;SCHEMBL9551685;DTXSID90497546

Chemical Property of 2-(2-Hydroxyethoxy)ethyl decanoate

Chemical Property:

• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 14
• Exact Mass: 260.19875937
• Heavy Atom Count: 18
• Complexity: 183

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCC(=O)OCCOCCO

Technology Process of 2-(2-Hydroxyethoxy)ethyl decanoate

There total 3 articles about 2-(2-Hydroxyethoxy)ethyl decanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2-(2-benzyloxyethoxy)ethyl decanoate (1430196-47-6) → 2-(2-benzyloxyethoxy)ethyl decanoate (7735-31-1,61596-57-4)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethyl acetate; at 40 ℃; for 24h;

DOI:10.1016/j.steroids.2013.02.001

Reference yield:

n-decanoyl chloride (112-13-0) → 2-(2-benzyloxyethoxy)ethyl decanoate (7735-31-1,61596-57-4)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap; pyridine / dichloromethane / 2 h / 0 - 22 °C / Inert atmosphere

2: palladium 10% on activated carbon; hydrogen / ethyl acetate / 24 h / 40 °C

With pyridine; dmap; palladium 10% on activated carbon; hydrogen; In dichloromethane; ethyl acetate;

DOI:10.1016/j.steroids.2013.02.001

Reference yield:

→ 2-(2-benzyloxyethoxy)ethyl decanoate (7735-31-1,61596-57-4)

Guidance literature:

Diethylglykol (Ueberschuss 14 : 1), Kaprinsaeure, Xyxlol, Kationenaustauscher, ca. 10h Δ 140 - 150gradC;

upstream raw materials:

n-decanoyl chloride

2-(2-benzyloxyethoxy)ethyl decanoate

Downstream raw materials:

benzyl 3α-{3-[2-(2-decanoyloxyethoxy)ethoxycarbonyl]propanoyloxy}-7α,12α-dihydroxy-5β-cholan-24-oate

Refernces

• 1、 -. "Combinatorial synthesis of PEG oligomer libraries". Page/Page column 11. . Retrieved 2010/02/15.