4-TRIFLUOROMETHYL-2,3,5,6-TETRAFLUOROTHIOPHENOL

Base Information

• Chemical Name: 4-TRIFLUOROMETHYL-2,3,5,6-TETRAFLUOROTHIOPHENOL
• CAS No.: 651-84-3
• Molecular Formula: C7HF7S
• Molecular Weight: 250.14
• Hs Code.: 29309099
• Mol file: 651-84-3.mol

Synonyms:4-(Trifluoromethyl)-2, 3, 5, 6-tetrafluorothiophenol;

Chemical Property of 4-TRIFLUOROMETHYL-2,3,5,6-TETRAFLUOROTHIOPHENOL

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 2.04mmHg at 25°C
• Refractive Index: 1.442-1.444
• Boiling Point: 169.5 °C at 760 mmHg
• PKA: 2.83±0.50(Predicted)
• Flash Point: 60 °C
• PSA: 38.80000
• Density: 1.641 g/cm³
• LogP: 3.55050

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,3,5,6-Tetrafluoro-4-(trifluoromethyl)benzenethiol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-TRIFLUOROMETHYL-2,3,5,6-TETRAFLUOROTHIOPHENOL

There total 3 articles about 4-TRIFLUOROMETHYL-2,3,5,6-TETRAFLUOROTHIOPHENOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

fluorochloromethyl 2,3,5,6-tetrafluoro-4-trifluoromethylphenyl sulfide → 1,2,4,5-tetrafluoro-3-(trifluoromethyl)benzene (651-80-9) + 4-trifluoromethyl-2,3,5,6-tetrafluorothiophenol (651-84-3)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; water; at 55 ℃; for 6h;

DOI:10.1134/S1070428015110068

Reference yield:

sodium sulfide (1313-82-2) + perfluorotoluene (434-64-0) → 4-trifluoromethyl-2,3,5,6-tetrafluorothiophenol (651-84-3)

Guidance literature:

In pyridine; ethylene glycol;

DOI:10.1039/jr9620001801

Reference yield:

→ 4-trifluoromethyl-2,3,5,6-tetrafluorothiophenol (651-84-3)

Guidance literature:

Darst.;

upstream raw materials:

sodium sulfide

perfluorotoluene

Downstream raw materials:

2,3,5,6-tetrafluoro-4-trifluoromethylphenylsulfenyl chloride

bis(2,3,5,6-tetrafluoro-4-trifluoromethylphenyl) sulfide

1,2,4,5-tetrafluoro-3-(trifluoromethyl)benzene

1,1′-disulfanediylbis[2,3,5,6-tetrafluoro-4-(trifluoromethyl)benzene]

Refernces