2-Furancarboxylic acid, 3-(2-methylpiperidino)propyl ester, hydrochloride

Base Information

• Chemical Name: 2-Furancarboxylic acid, 3-(2-methylpiperidino)propyl ester, hydrochloride
• CAS No.: 67227-32-1
• Molecular Formula: C14H22ClNO3
• Molecular Weight: 287.7824
• DSSTox Substance ID: DTXSID20986357
• Mol file: 67227-32-1.mol

Synonyms:2-Furoic acid, 3'-(2''-methylpiperidino)propyl ester, hydrochloride;2-Furancarboxylic acid, 3-(2-methylpiperidino)propyl ester, hydrochloride;67227-32-1;DTXSID20986357;LS-70798;2-Furancarboxylic acid, 3-(2-methyl-1-piperidinyl)propyl ester, hydrochloride;3-(2-Methylpiperidin-1-yl)propyl furan-2-carboxylate--hydrogen chloride (1/1)

Chemical Property of 2-Furancarboxylic acid, 3-(2-methylpiperidino)propyl ester, hydrochloride

Chemical Property:

• Vapor Pressure: 3.94E-05mmHg at 25°C
• Boiling Point: 352°Cat760mmHg
• Flash Point: 166.7°C
• Density: g/cm³
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 287.1288213
• Heavy Atom Count: 19
• Complexity: 270

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCCCN1CCCOC(=O)C2=CC=CO2.Cl

Technology Process of 2-Furancarboxylic acid, 3-(2-methylpiperidino)propyl ester, hydrochloride

There total 2 articles about 2-Furancarboxylic acid, 3-(2-methylpiperidino)propyl ester, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Methylpiperidin (109-05-7,3000-79-1) → furan-2-carboxylic acid-[3-(2-methyl-piperidino)-propylester]; hydrochloride (67227-32-1)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / 160 °C

2: benzene

With potassium carbonate; benzene;

DOI:10.1021/ja01216a051

Reference yield:

2-methylpiperidine-1-propanol (94-88-2) + 2-furancarbonyl chloride (527-69-5) → furan-2-carboxylic acid-[3-(2-methyl-piperidino)-propylester]; hydrochloride (67227-32-1)

Guidance literature:

With benzene;

DOI:10.1021/ja01216a051

upstream raw materials:

2-methylpiperidine-1-propanol

2-furancarbonyl chloride

2-Methylpiperidin