Dodecanamide, N-(4-methoxyphenyl)-

Base Information

• Chemical Name: Dodecanamide, N-(4-methoxyphenyl)-
• CAS No.: 78398-24-0
• Molecular Formula: C19H31NO2
• Molecular Weight: 305.461
• Mol file: 78398-24-0.mol

Synonyms:

Chemical Property of Dodecanamide, N-(4-methoxyphenyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Dodecanamide, N-(4-methoxyphenyl)-

There total 4 articles about Dodecanamide, N-(4-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

lauric acid (143-07-7) + 4-methoxy-aniline (104-94-9) → N-(4-methoxyphenyl)dodecanamide (78398-24-0)

Guidance literature:

With niobium(V) oxide; In toluene; for 30h; Reflux; Inert atmosphere;

DOI:10.1002/cctc.201500672

Reference yield: 78.0%

thiododecanoic acid + 4-methoxy-aniline (104-94-9) → N-(4-methoxyphenyl)dodecanamide (78398-24-0)

Guidance literature:

With copper(ll) sulfate pentahydrate; In methanol; at 20 ℃; for 0.0833333h;

DOI:10.1021/jo400701v

Reference yield:

lauric acid (143-07-7) → N-(4-methoxyphenyl)dodecanamide (78398-24-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1-hydroxy-pyrrolidine-2,5-dione; sodium hydrogen sulfide

2: copper(ll) sulfate pentahydrate / methanol / 0.08 h / 20 °C

With sodium hydrogen sulfide; 1-hydroxy-pyrrolidine-2,5-dione; copper(ll) sulfate pentahydrate; In methanol;

DOI:10.1021/jo400701v

upstream raw materials:

n-dodecanoyl chloride

4-methoxy-aniline

lauric acid

Refernces

• 1、 Yildirim, Ayhan. "Metallic magnesium: an efficient catalyst toward N-aryl and N-alkyl substituted amides directly from aliphatic carboxylic acids". . p. 947 - 951. Retrieved 2015/08/06.