Cyclobutane, (chloromethyl)-

Base Information

• Chemical Name: Cyclobutane, (chloromethyl)-
• CAS No.: 78415-89-1
• Molecular Formula: C5H9Cl
• Molecular Weight: 104.579
• Mol file: 78415-89-1.mol

Synonyms:

Chemical Property of Cyclobutane, (chloromethyl)-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclobutane, (chloromethyl)-

There total 3 articles about Cyclobutane, (chloromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

cyclobutylmethyl 4-methylbenzenesulfonate (13295-53-9) → cyclobutylmethyl chloride (78415-89-1)

Guidance literature:

With lithium chloride; In N,N,N,N,N,N-hexamethylphosphoric triamide; for 15h; Ambient temperature; Other solvent: DMF_.;

Reference yield:

cyclobutanemethanol (4415-82-1) → cyclobutylmethyl chloride (78415-89-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / pyridine / 24 h / 0 °C

2: 97 percent / LiCl / hexamethylphosphoric acid triamide / 15 h / Ambient temperature; Other solvent: DMF_.

With lithium chloride; In pyridine; N,N,N,N,N,N-hexamethylphosphoric triamide;

Reference yield:

→ cyclobutylmethyl chloride (78415-89-1)

Guidance literature:

Aus Cyclobutylmethanol u. SOCl2 i. Ggw. v. (C2H5)3N; anfangs in Ae., dann ohne Lsgm., 90grad;

upstream raw materials:

cyclobutylmethyl 4-methylbenzenesulfonate

cyclobutanemethanol

Downstream raw materials:

(-)-3-acetyl-N-(cyclobutylmethyl)morphinan

1-penten

methyl-cyclobutane

cyclobutylmethyl iodide

Refernces