(2H4)Urea

Base Information

• Chemical Name: (2H4)Urea
• CAS No.: 1433-11-0
• Molecular Formula: CD4 N2 O
• Molecular Weight: 64.0238
• European Community (EC) Number: 215-857-8
• DSSTox Substance ID: DTXSID00162379
• Mol file: 1433-11-0.mol

Synonyms:Urea-d4;1433-11-0;1,1,3,3-tetradeuteriourea;(2H4)Urea;EINECS 215-857-8;Urea D4;(?H?)urea;CD4N2O;Urea-d4, 98 atom % D;C-D4-N2-O;DTXSID00162379;HY-Y0271S1;MFCD00044227;AKOS015913207;CS-T-62643;CS-0534877;D98928

Chemical Property of (2H4)Urea

Chemical Property:

• Vapor Pressure: 0.395mmHg at 25°C
• Melting Point: 132-135oC(lit.)
• Boiling Point: 196.6°Cat760mmHg
• Flash Point: 72.7°C
• PSA: 69.11000
• Density: 1.212g/cm³
• LogP: 0.42440
• Storage Temp.: Room Temperature, Under inert atmosphere
• Solubility.: DMSO (Sparingly, Sonicated), Methanol (Slightly), Water (Slightly)
• XLogP3: -1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 64.057469739
• Heavy Atom Count: 4
• Complexity: 29

Purity/Quality:

99%, ^*data from raw suppliers

Urea-d4 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 36/37/38-40
• Safety Statements: 22-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(=O)(N)N
• Isomeric SMILES: [2H]N([2H])C(=O)N([2H])[2H]
• Uses: Labelled Urea. Physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient ; diuretic. Labelled Urea. Physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diuretic.

Technology Process of (2H4)Urea

There total 3 articles about (2H4)Urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

urea (57-13-6) → urea-d4 (1433-11-0)

Guidance literature:

With water-d2;

DOI:10.1107/S0567740880005420

Reference yield:

water-d2 (7789-20-0) + urea (57-13-6) → urea-d4 (1433-11-0)

Guidance literature:

dissolving urea in D2O and evapg. excess of D2O repeatedly;

Reference yield:

→ urea-d4 (1433-11-0)

Guidance literature:

DOI:10.1080/00268976100100171

upstream raw materials:

urea

water-d2

Refernces

• 1、 Weber, H. P.,Ruble, J. R.,Craven, B. M.,McMullan, R. K.. "The Neutron Structure at 116 K of the 1:1 Complex of Perdeuterated Parabanic Acid and Urea". . p. 1121 - 1126. Retrieved 1980.
• 2、 Yang, Xiaorong,Müller, Klaus. "The guest ordering and dynamics in urea inclusion compounds studied by solid-state 1H and 13C MAS NMR spectroscopy". . p. 113 - 120. Retrieved 2011.
• 3、 Gilson,McDowell. "-". . p. 125,126. Retrieved 1961.