1-Allylcyclopropanecarboxylic acid

Base Information

• Chemical Name: 1-Allylcyclopropanecarboxylic acid
• CAS No.: 80360-57-2
• Molecular Formula: C7H10O2
• Molecular Weight: 126.155
• Hs Code.: 2916209090
• Mol file: 80360-57-2.mol

Synonyms:1-Allylcyclopropanecarboxylic acid;1-allyl-cyclopropane-1-carboxylic acid;1-(2-Propenyl)cyclopropancarbonsaeure;1-allylcyclopropancarbonsaeure;

Chemical Property of 1-Allylcyclopropanecarboxylic acid

Chemical Property:

• PSA: 37.30000
• LogP: 1.42730

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Allylcyclopropanecarboxylicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Allylcyclopropanecarboxylic acid

There total 4 articles about 1-Allylcyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-allyl-cyclopropanecarboxylic acid tert-butyl ester (108546-98-1) → 1-(2-Propenyl)cyclopropancarbonsaeure (80360-57-2)

Guidance literature:

With trifluoroacetic acid;

Reference yield:

allyl bromide (106-95-6) + cyclopropanecarboxylic acid (1759-53-1) → 1-(2-Propenyl)cyclopropancarbonsaeure (80360-57-2)

Guidance literature:

With lithium diisopropyl amide; Yield given. Multistep reaction; 1.) THF, 0 deg C, 10 min, 2.) room temperature, 3 h;

DOI:10.1021/jo00344a030

Reference yield:

1-(2-Propenyl)cyclopropancarbonsaeure-methylester (106434-82-6) → 1-(2-Propenyl)cyclopropancarbonsaeure (80360-57-2)

Guidance literature:

1-(2-Propenyl)cyclopropancarbonsaeure-methylester; With sodium hydroxide; In methanol; water; Reflux;

With hydrogenchloride; water;

DOI:10.1016/j.tetlet.2020.152620

upstream raw materials:

C₄H₄LiO₂^(1-)*Li⁽¹⁺⁾

allyl bromide

cyclopropanecarboxylic acid

1-allyl-cyclopropanecarboxylic acid tert-butyl ester

Downstream raw materials:

2-Ethylpentansaeure-methylester

1-Propyl-cyclopropanecarboxylic acid methyl ester

1-(2-Propenyl)cyclopropancarbonsaeure-methylester

2-ethylvaleric acid

Refernces

• 1、 Deng, Xiaojun,Zhang, Luwen,Liu, Huixia,Bai, Yu,He, Wei. "mCPBA-mediated dioxygenation of unactivated alkenes for the synthesis of 5-imino-2-tetrahydrofuranyl methanol derivatives". supporting information. . Retrieved 2020/11/24.
• 2、 -. "Ortho-substituted benzyl esters of cyclopropanecarboxylic acids". . . Retrieved 2008/06/13.