1-Allyl-1,2,3,4-tetrahydroquinoline

Base Information

• Chemical Name: 1-Allyl-1,2,3,4-tetrahydroquinoline
• CAS No.: 80574-15-8
• Molecular Formula: C12H15N
• Molecular Weight: 173.258
• DSSTox Substance ID: DTXSID70508462
• Nikkaji Number: J1.692.251J
• Wikidata: Q82365397
• Mol file: 80574-15-8.mol

Synonyms:1-Allyl-1,2,3,4-tetrahydroquinoline;80574-15-8;SCHEMBL4631036;DTXSID70508462;1-(Prop-2-en-1-yl)-1,2,3,4-tetrahydroquinoline

Chemical Property of 1-Allyl-1,2,3,4-tetrahydroquinoline

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 173.120449483
• Heavy Atom Count: 13
• Complexity: 176

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCN1CCCC2=CC=CC=C21

Technology Process of 1-Allyl-1,2,3,4-tetrahydroquinoline

There total 1 articles about 1-Allyl-1,2,3,4-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3,4-dihydro-2H-quinoline-1-carboxylic acid allyl ester → 1,2,3,4-tetrahydroisoquinoline (635-46-1) + N-allyl-1,2,3,4-tetrahydroquinoline (80574-15-8)

Guidance literature:

With aminomethyl resin-supported N-propylbarbituric acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 - 40 ℃; for 1h;

DOI:10.1055/s-2003-39907

Reference yield: 86.0%

N-allyl-1,2,3,4-tetrahydroquinoline (80574-15-8) → 1,2,3,4-tetrahydroisoquinoline (635-46-1)

Guidance literature:

With aminomethyl resin-supported N-propylbarbituric acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 40 ℃;

DOI:10.1055/s-2003-39907

Reference yield: 64.0%

terephthalonitrile (623-26-7) + N-allyl-1,2,3,4-tetrahydroquinoline (80574-15-8) → 4-(1-allyl-1,2,3,4-tetrahydroquinolin-2-yl)benzonitrile

Guidance literature:

With diethylacetamide; caesium carbonate; for 40h; Irradiation; Green chemistry;

DOI:10.1021/acs.orglett.1c00984

Downstream raw materials:

1,2,3,4-tetrahydroisoquinoline

1-(1,2,3,4-Tetrahydro-quinolin-8-yl)-propan-2-ol

6-allyl-1,2,3,4-tetrahydroquinoline

8-allyl-1,2,3,4-tetrahydroquinoline

Refernces