Benzenebutanesulfonyl azide

Base Information

• Chemical Name: Benzenebutanesulfonyl azide
• CAS No.: 80639-69-6
• Molecular Formula: C10H13N3O2S
• Molecular Weight: 239.298
• Mol file: 80639-69-6.mol

Synonyms:

Chemical Property of Benzenebutanesulfonyl azide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenebutanesulfonyl azide

There total 3 articles about Benzenebutanesulfonyl azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-phenylbutane-1-sulfonyl chloride (88107-02-2) → 4-phenyl-1-butanesulphonyl azide (80639-69-6)

Guidance literature:

With sodium azide; In water; acetone; for 3h;

DOI:10.1021/jacs.9b08894

Reference yield:

C10H13O3S(1-)*C16H36N(1+) → 4-phenyl-1-butanesulphonyl azide (80639-69-6)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide; bis(trichloromethyl) carbonate / dichloromethane / 1 h / 0 - 20 °C

2: sodium azide / water; acetone / 3 h

With sodium azide; bis(trichloromethyl) carbonate; N,N-dimethyl-formamide; In dichloromethane; water; acetone;

DOI:10.1021/jacs.9b08894

Reference yield:

1-Bromo-4-phenylbutane (13633-25-5) → 4-phenyl-1-butanesulphonyl azide (80639-69-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium sulfite / water; ethanol / 12 h / 100 °C

1.2: 0.5 h

2.1: N,N-dimethyl-formamide; bis(trichloromethyl) carbonate / dichloromethane / 1 h / 0 - 20 °C

3.1: sodium azide / water; acetone / 3 h

With sodium azide; bis(trichloromethyl) carbonate; N,N-dimethyl-formamide; sodium sulfite; In ethanol; dichloromethane; water; acetone;

DOI:10.1021/jacs.9b08894

upstream raw materials:

4-phenylbutane-1-sulfonyl chloride

1-Bromo-4-phenylbutane

Downstream raw materials:

4-Phenylbut-1-ene

4-phenyl-1-butanesulphonamide

Refernces

• 1、 McManus, Samuel P.,Smith, Maurice R.,Abramovitch, Rudolph A.,Offor, Mercy N.. "Thermolysis of Sulfonyl Azides Bearing Nucleophilic Neighboring Groups. A Search for Anchimeric Assistance". . p. 683 - 687. Retrieved 2007/10/02.