Technology Process of 2,5-Cyclohexadiene-1,4-dione,
2-(12-hydroxy-5,8-dodecadiynyl)-3,5,6-trimethyl-
There total 11 articles about 2,5-Cyclohexadiene-1,4-dione,
2-(12-hydroxy-5,8-dodecadiynyl)-3,5,6-trimethyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ammonium cerium(IV) nitrate;
In
water; acetonitrile;
at 0 - 2 ℃;
for 0.666667h;
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 90 percent / 70percent perchloric acid, hydrogen / 5percent palladium-charcoal / acetic acid / 1.5 h / 70 °C
2: triethylamine / CH2Cl2 / 1 h / -5 °C
3: sodium iodide / acetone / 2 h / 50 °C
4: 1.) sodium amide / 1.) Et2O, liquid ammonia, -50 deg C - -40 deg C, 60 min, 2.) -50 deg C - -40 deg C, 100 min
5: toluene-p-sulphonic acid / methanol / 0.5 h / 70 °C
6: triethylamine / CH2Cl2 / 1 h / -5 °C
7: sodium iodide / acetone / 2 h / 50 °C
8: 1.) ethyl magnesium bromide, copper(I) bromide / 1.) THF, 2.) 50 deg C, 2 h
9: toluene-p-sulphonic acid / methanol / 0.5 h / 70 °C
10: 75 percent / cerium(IV) ammonium nitrate / acetonitrile; H2O / 0.67 h / 0 - 2 °C
With
perchloric acid; ammonium cerium(IV) nitrate; ethylmagnesium bromide; hydrogen; toluene-4-sulfonic acid; sodium amide; triethylamine; sodium iodide; copper(I) bromide;
palladium on activated charcoal;
In
methanol; dichloromethane; water; acetic acid; acetone; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) ethyl magnesium bromide, copper(I) bromide / 1.) THF, 2.) 50 deg C, 2 h
2: toluene-p-sulphonic acid / methanol / 0.5 h / 70 °C
3: 75 percent / cerium(IV) ammonium nitrate / acetonitrile; H2O / 0.67 h / 0 - 2 °C
With
ammonium cerium(IV) nitrate; ethylmagnesium bromide; toluene-4-sulfonic acid; copper(I) bromide;
In
methanol; water; acetonitrile;