Glycine, N-(carboxymethyl)-N-[2-(2,6-dioxo-4-morpholinyl)ethyl]-

Base Information

• Chemical Name: Glycine, N-(carboxymethyl)-N-[2-(2,6-dioxo-4-morpholinyl)ethyl]-
• CAS No.: 81329-81-9
• Molecular Formula: C10H14N2O7
• Molecular Weight: 274.23
• DSSTox Substance ID: DTXSID60382814
• Nikkaji Number: J2.514.226H
• Wikidata: Q82174261
• Mol file: 81329-81-9.mol

Synonyms:81329-81-9;2-[carboxymethyl-[2-(2,6-dioxomorpholin-4-yl)ethyl]amino]acetic Acid;Glycine, N-(carboxymethyl)-N-[2-(2,6-dioxo-4-morpholinyl)ethyl]-;SCHEMBL2809739;DTXSID60382814;Ethylenediamine-N,N,N',N'-tetraacetic Acid Monoanhydride;FT-0668252;[[2-(2,6-Dioxomorpholino)ethyl]imino]diacetic acid

Chemical Property of Glycine, N-(carboxymethyl)-N-[2-(2,6-dioxo-4-morpholinyl)ethyl]-

Chemical Property:

• Melting Point: 195°C dec.
• PSA: 124.45000
• LogP: -2.21910
• Solubility.: DMF, DMSO, Water (with slight heating)
• XLogP3: -5.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 7
• Exact Mass: 274.08010079
• Heavy Atom Count: 19
• Complexity: 363

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1C(=O)OC(=O)CN1CCN(CC(=O)O)CC(=O)O
• Uses: Ethylenediamine-N,N,N’,N’-tetraacetic Acid Monoanhydride_x000D_Discontinued (cas# 81329-81-9) is a compound useful in organic synthesis.

Technology Process of Glycine, N-(carboxymethyl)-N-[2-(2,6-dioxo-4-morpholinyl)ethyl]-

There total 1 articles about Glycine, N-(carboxymethyl)-N-[2-(2,6-dioxo-4-morpholinyl)ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.5%

ethylenediaminetetraacetic dianhydride (23911-25-3) → EDTA monoanhydride (81329-81-9)

Guidance literature:

With water; In N,N-dimethyl-formamide; at 70 - 72 ℃; for 3h;

Reference yield: 87.9%

Cabazitaxel (1714967-27-7) + EDTA monoanhydride (81329-81-9) → C55H71N3O21

Guidance literature:

With dmap; triethylamine; In 1-methyl-pyrrolidin-2-one; at 10 ℃; for 48h; Solvent; Temperature;

Reference yield:

C59H80N11O11Pol + EDTA monoanhydride (81329-81-9) → C69H94N13O18Pol

Guidance literature:

In N,N-dimethyl-formamide; for 15h; solid phase reaction;

DOI:10.1039/c0ob00309c

upstream raw materials:

ethylenediaminetetraacetic dianhydride

Refernces

• 1、 Rieter, William J.,Taylor, Kathryn M. L.,Lin, Wenbin. "Surface modification and functionalization of nanoscale metal-organic frameworks for controlled release and luminescence sensing". . p. 9852 - 9853. Retrieved 2007.
• 2、 Mayor, Marcel,Scheffold, Rolf,Walder, Lorenz. "90. Synthesis of Vitamin B12 Derivatives with a Peripheral Metal Binding Site". . p. 1183 - 1189. Retrieved 2007/10/03.