Benzenepentanoic acid, 4-(methylthio)-

Base Information

• Chemical Name: Benzenepentanoic acid, 4-(methylthio)-
• CAS No.: 817166-89-5
• Molecular Formula: C12H16O2S
• Molecular Weight: 224.324
• Mol file: 817166-89-5.mol

Synonyms:

Chemical Property of Benzenepentanoic acid, 4-(methylthio)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenepentanoic acid, 4-(methylthio)-

There total 5 articles about Benzenepentanoic acid, 4-(methylthio)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-(4-bromobutyl)phenyl)(methyl)sulfane + carbon dioxide (124-38-9,18923-20-1) → 5-(4-methylthiophenyl)pentanoic acid (817166-89-5)

Guidance literature:

(4-(4-bromobutyl)phenyl)(methyl)sulfane; With iodine; magnesium; In diethyl ether; at 20 ℃;

carbon dioxide; In diethyl ether;

DOI:10.1002/chem.200400516

Reference yield:

(4-bromophenyl)thioanisole (104-95-0) → 5-(4-methylthiophenyl)pentanoic acid (817166-89-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-BuLi / hexane; diethyl ether / 2 h

1.2: 1.843 g / hexane; diethyl ether

2.1: I₂; Mg / diethyl ether / 20 °C

2.2: 150 mg / diethyl ether

With n-butyllithium; iodine; magnesium; In diethyl ether; hexane;

DOI:10.1002/chem.200400516

Reference yield:

5-(4-methylsulfanyl-phenyl)-5-oxo-valeric acid (845790-49-0) → 5-(4-methylthiophenyl)pentanoic acid (817166-89-5)

Guidance literature:

With hydrogenchloride; amalgamated zinc;

upstream raw materials:

5-(4-methylsulfanyl-phenyl)-5-oxo-valeric acid

carbon dioxide

(4-bromophenyl)thioanisole

ethyl glutaroyl chloride

Refernces