2-(4-Hydroxyphenyl)oxirane

Base Information

• Chemical Name: 2-(4-Hydroxyphenyl)oxirane
• CAS No.: 93835-83-7
• Molecular Formula: C8H8O2
• Molecular Weight: 136.15
• DSSTox Substance ID: DTXSID30917677
• Nikkaji Number: J2.845.300K
• Mol file: 93835-83-7.mol

Synonyms:4-hydroxystyrene 7,8-oxide

Chemical Property of 2-(4-Hydroxyphenyl)oxirane

Chemical Property:

• Vapor Pressure: 0.00302mmHg at 25°C
• Refractive Index: 1.611
• Boiling Point: 275.5 °C at 760 mmHg
• Flash Point: 135.2 °C
• PSA: 32.76000
• Density: 1.273 g/cm³
• LogP: 1.46350
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 136.052429494
• Heavy Atom Count: 10
• Complexity: 116

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(O1)C2=CC=C(C=C2)O
• Uses: 4-hydroxystyrene 7,8-oxide is used in the enzymic preparation of self-crosslinking hydroxyphenyl epoxy compounds.

Technology Process of 2-(4-Hydroxyphenyl)oxirane

There total 1 articles about 2-(4-Hydroxyphenyl)oxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → (-)-4-hydroxyphenyloxirane (93835-83-7) + phenylacetaldehyde (122-78-1) + benzaldehyde (100-52-7)

Guidance literature:

With iodobenzene; Oxone; C₄₈H₂₄ClFeN₄O₈^(4-)*4Na⁽¹⁺⁾; In water; acetonitrile; at 20 ℃; for 1h;

DOI:10.1002/adsc.201000172

Reference yield: 87.0%

(-)-4-hydroxyphenyloxirane (93835-83-7) → 1-(4-hydroxyphenyl)ethanol (93453-79-3,166164-76-7,2380-91-8)

Guidance literature:

With diphosphorus tetraiodide; tetraethylammonium bromide; water; In dichloromethane; at 20 ℃; for 5h; regioselective reaction;

DOI:10.1080/00397910903219492

upstream raw materials:

styrene

Downstream raw materials:

1-(4-hydroxyphenyl)ethanol

Refernces