Ethyl 2-acetyloxypropanoate

Base Information

• Chemical Name: Ethyl 2-acetyloxypropanoate
• CAS No.: 2985-28-6
• Molecular Formula: C7H12 O4
• Molecular Weight: 160.17
• European Community (EC) Number: 608-421-7
• NSC Number: 5224
• DSSTox Substance ID: DTXSID00277952
• Nikkaji Number: J262.250E
• Mol file: 2985-28-6.mol

Synonyms:ethyl 2-acetyloxypropanoate;2985-28-6;ethyl acetyl lactate;NSC 5224;ETHYL 2-(ACETYLOXY)PROPANOATE;ethyl 2-acetoxypropanoate;2-acetoxypropionic acid ethyl ester;NSC5224;SCHEMBL725208;DTXSID00277952;2-Acetoxypropanoic acid ethyl ester;NSC-5224;Propanoic acid, 2-(acetyloxy)-, ethyl ester

Chemical Property of Ethyl 2-acetyloxypropanoate

Chemical Property:

• Vapor Pressure: 0.451mmHg at 25°C
• Refractive Index: 1.4260 (estimate)
• Boiling Point: 194°Cat760mmHg
• Flash Point: 87.4°C
• PSA: 52.60000
• Density: 1.057g/cm³
• LogP: 0.50110
• Water Solubility.: 33.7g/L(25 oC)
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 160.07355886
• Heavy Atom Count: 11
• Complexity: 153

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(C)OC(=O)C

Technology Process of Ethyl 2-acetyloxypropanoate

There total 2 articles about Ethyl 2-acetyloxypropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

(C4H9)3SnOCH(CH3)COOC2H5 + acetyl chloride (75-36-5) → ethyl 2-acetoxypropanoate (2985-28-6) + tributyltin chloride (1461-22-9)

Guidance literature:

Reference yield:

ethyl 2-hydroxypropionate (97-64-3,2676-33-7) + acetic acid (64-19-7,77671-22-8) → 2-acetoxypropionic acid (535-17-1) + ethyl 2-acetoxypropanoate (2985-28-6)

Guidance literature:

With sulfuric acid; benzene;

Reference yield:

ethyl 2-acetoxypropanoate (2985-28-6) → ethyl acrylate (140-88-5,9003-32-1)

Guidance literature:

With quartz; at 450 ℃;

DOI:10.1039/jr9350000400

upstream raw materials:

ethyl 2-hydroxypropionate

acetic acid

acetyl chloride

Downstream raw materials:

acetaldehyde

ethene

ethyl acrylate

Refernces