2,2'-((3-Methoxyphenyl)azanediyl)diethanol

Base Information

• Chemical Name: 2,2'-((3-Methoxyphenyl)azanediyl)diethanol
• CAS No.: 17126-75-9
• Molecular Formula: C11H17NO3
• Molecular Weight: 211.261
• Hs Code.: 2922509090
• DSSTox Substance ID: DTXSID80370137
• Nikkaji Number: J141.512C
• Wikidata: Q72445965
• Mol file: 17126-75-9.mol

Synonyms:17126-75-9;2,2'-((3-Methoxyphenyl)azanediyl)diethanol;N,N-BIS(2-HYDROXYETHYL)-3-METHOXYANILINE;2-[N-(2-hydroxyethyl)-3-methoxyanilino]ethanol;NN-BIS(2-HYDROXYETHYL)-3-METHOXYANILINE;3-[Di(2-hydroxyethyl)amino]anisole;Ethanol, 2,2'-[(3-methoxyphenyl)imino]bis-;2-[(2-hydroxyethyl)(3-methoxyphenyl)amino]ethan-1-ol;SCHEMBL4932784;DTXSID80370137;AKOS016001345;SB78713;2,2'-(3-methoxyphenylazanediyl)diethanol;BS-52933;CS-0188180;E75879;A881939;2,2'-[(3-Methoxyphenyl)azanediyl]di(ethan-1-ol)

Chemical Property of 2,2'-((3-Methoxyphenyl)azanediyl)diethanol

Chemical Property:

• Appearance/Colour: white crystalline needles or powder
• Vapor Pressure: 2.5E-06mmHg at 25°C
• Melting Point: 49-50℃
• Refractive Index: 1.5718 (589.3 nm 25℃)
• Boiling Point: 376.2 °C at 760 mmHg
• Flash Point: 181.3 °C
• PSA: 52.93000
• Density: 1.177g/cm³
• LogP: 0.48620
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 211.12084340
• Heavy Atom Count: 15
• Complexity: 160

Purity/Quality:

99.90% ^*data from raw suppliers

2,2'-((3-Methoxyphenyl)azanediyl)diethanol 95+% ^*data from reagent suppliers

Safty Information:

• Safety Statements: S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC(=C1)N(CCO)CCO

Technology Process of 2,2'-((3-Methoxyphenyl)azanediyl)diethanol

There total 3 articles about 2,2'-((3-Methoxyphenyl)azanediyl)diethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

oxirane (75-21-8,99932-75-9) + m-Anisidine (536-90-3,918666-97-4) → 3-methoxy-bisaniline (17126-75-9)

Guidance literature:

With water; 45 h, rt., then 1 h, 70 deg C;

DOI:10.1016/S0022-1139(00)82776-1

Reference yield: 85.0%

m-Anisidine (536-90-3,918666-97-4) + 2-chloro-ethanol (107-07-3) → 3-methoxy-bisaniline (17126-75-9)

Guidance literature:

With calcium carbonate; potassium iodide; In water; for 8h; Reflux;

DOI:10.1016/j.bmcl.2010.12.052

Reference yield:

→ 3-methoxy-bisaniline (17126-75-9)

Guidance literature:

3-Methoxy-anilin, 2-Chlor-aethanol, CaCO3;

upstream raw materials:

oxirane

m-Anisidine

2-chloro-ethanol

Downstream raw materials:

3-methoxy-bisaniline

4'-(3-methoxyphenyl)spiro[indoline-1,1'-piperazin]-1-ium chloride

N,N-bis(2-(methylsulfonyloxy)ethyl)-3-methoxylaniline

1,4-dioxa-7,13-dithia-10-(3-methoxyphenyl)-10-azacyclopentadecane

Refernces

• 1、 Palmer, Brian D.,Wilson, William R.,Pullen, Susan M.,Denny, William A.. "Hypoxia-Selective Antitumor Agents. 3. Relationships between Structure and Cytotoxicity against Cultured Tumor Cells for Substituted N,N-Bis(2-chloroethyl)anilines". . p. 112 - 121. Retrieved 2007/10/02.