2-Thiazolin-4-one, 2-hydrazino-

Base Information

• Chemical Name: 2-Thiazolin-4-one, 2-hydrazino-
• CAS No.: 32003-36-4
• Molecular Formula: C3H5 N3 O S
• Molecular Weight: 131.16
• Hs Code.: 2934100090
• Mol file: 32003-36-4.mol

Synonyms:2,4-Thiazolidinedione,2-hydrazone (6CI,9CI); 2-Thiazolin-4-one, 2-hydrazino- (8CI);2-Hydrazino-4(5H)-thiazolone; 2-Hydrazino-4-oxo-2-thiazoline;2-Hydrazono-4-thiazolidinone

Chemical Property of 2-Thiazolin-4-one, 2-hydrazino-

Chemical Property:

• Vapor Pressure: 0.00611mmHg at 25°C
• Melting Point: 296-298 °C (decomp)
• Boiling Point: 272.3°Cat760mmHg
• PKA: 11.13±0.20(Predicted)
• Flash Point: 118.5°C
• PSA: 96.27000
• Density: 1.87g/cm³
• LogP: 0.05530

Purity/Quality:

99%min ^*data from raw suppliers

2-HYDRAZINYL-4(5H)-THIAZOLONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Thiazolin-4-one, 2-hydrazino-

There total 5 articles about 2-Thiazolin-4-one, 2-hydrazino- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

thiosemicarbazide (79-19-6) + chloroacetic acid (79-11-8) → 2-hydrazino-1,3-thiazol-4(5H)-one (32003-36-4)

Guidance literature:

for 0.116667h; microwave irradiation;

DOI:10.1080/104265090968992

Reference yield: 41.0%

thiosemicarbazide (79-19-6) + chloroacetic acid (79-11-8) → 1-amino-2-thioxo-5-imidazolidinone (117829-36-4) + 4-Oxothiazolidin-2-hydrazon (32003-36-4) + 1-amino-2-thioxo-imidazolidin-4-one (17352-41-9)

Guidance literature:

With acetic acid; Reflux;

DOI:10.1039/c3ra47680d

Reference yield:

2-thioxo-4-thiazolidinone (141-84-4) → 4-Oxothiazolidin-2-hydrazon (32003-36-4)

Guidance literature:

With ethanol; hydrazine hydrate;

upstream raw materials:

2-thioxo-4-thiazolidinone

monochloroacetic acid anhydride

thiosemicarbazide hydrochloride

thiosemicarbazide

Downstream raw materials:

5-[1-Phenyl-meth-(E)-ylidene]-2-{N'-[1-phenyl-meth-(E)-ylidene]-hydrazino}-thiazol-4-one

2-hydrazino-7-(4-nitro-phenyl)-5-oxo-5H-pyrano[2,3-d]thiazole-6-carbothioic acid amide

2-hydrazino-7-(4-methoxy-phenyl)-5-oxo-5H-pyrano[2,3-d]thiazole-6-carbothioic acid amide

4-methoxy-benzaldehyde [5-(4-methoxy-benzylidene)-4-oxo-thiazolidin-2-ylidene]-hydrazone

Refernces

• 1、 Sathishkumar, Munusamy,Ramachandran, Gunasekar,Sathiyanarayanan, Kulathu Iyer. "Cyclododecanone as a recyclable protecting group for the synthesis of highly functionalized 3-amino-2-thiohydantoins from conventional starting materials". . p. 8498 - 8501. Retrieved 2014/03/21.