N'-(Diphenylmethylene)-4-methylbenzenesulfonohydrazide

Base Information

• Chemical Name: N'-(Diphenylmethylene)-4-methylbenzenesulfonohydrazide
• CAS No.: 4545-20-4
• Molecular Formula: C20H18N2O2S
• Molecular Weight: 350.441
• Hs Code.: 2935009090
• NSC Number: 120609,234744
• DSSTox Substance ID: DTXSID20298109
• Nikkaji Number: J460.960C
• Mol file: 4545-20-4.mol

Synonyms:4545-20-4;N'-(Diphenylmethylene)-4-methylbenzenesulfonohydrazide;Benzophenone tosylhydrazone;BENZOPHENONE TOSYLHYDRAZONE 97;N-(benzhydrylideneamino)-4-methylbenzenesulfonamide;N'-(Diphenylmethylidene)-4-methylbenzene-1-sulfonohydrazide;NSC120609;Benzophenone p-toluenesulfonylhydrazone;Benzophenone tosyl hydrazone;Benzophenone p-tosylhydrazone;SCHEMBL6636511;Benzophenone tosylhydrazone, 97%;DTXSID20298109;MFCD00381345;NSC234744;AKOS005103830;9N-501S;benzophenone p-toluenesulphonylhydrazone;NSC 120609;NSC 234744;NSC-120609;NSC-234744;CS-0323113;N'-(Diphenylmethylene)-4-methylbenzenesulfonohydrazide #

Chemical Property of N'-(Diphenylmethylene)-4-methylbenzenesulfonohydrazide

Chemical Property:

• Melting Point: 178-182oC(lit.)
• Boiling Point: 514.1°Cat760mmHg
• PKA: 8.61±0.40(Predicted)
• Flash Point: 264.7°C
• PSA: 66.91000
• Density: 1.17g/cm³
• LogP: 5.19760
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 350.10889899
• Heavy Atom Count: 25
• Complexity: 513

Purity/Quality:

99% ^*data from raw suppliers

N'-(Diphenylmethylene)-4-methylbenzenesulfonohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)NN=C(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of N'-(Diphenylmethylene)-4-methylbenzenesulfonohydrazide

There total 6 articles about N'-(Diphenylmethylene)-4-methylbenzenesulfonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

diethyl ether (60-29-7,927820-24-4) + toluene-4-sulfonic acid hydrazide (1576-35-8) → benzophenone tosylhydrazone (4545-20-4)

Guidance literature:

With benzophenone; In ethanol;

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → benzophenone tosylhydrazone (4545-20-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / water; tetrahydrofuran / 0.5 h / 0 °C

2: methanol / Reflux

With hydrazine hydrate; In tetrahydrofuran; methanol; water;

DOI:10.1039/c5cc07833d

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → benzophenone tosylhydrazone (4545-20-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate

2: ethanol / Heating

With hydrazine hydrate; In ethanol;

upstream raw materials:

Bicyclo<1.1.1>pent-1-ylphenylthioether

benzonitrile

toluene-4-sulfonic acid hydrazide

p-toluenesulfonyl chloride

Downstream raw materials:

benzhydryl morpholine-4-carbodithioate

2-(1-phenylbenzyl)pyridine N-oxide

(2-benzofuryl)diphenylmethane

2-(4-phenyl-2-tosyl-1,2-dihydrophthalazin-1-yl)acetonitrile

Refernces

• 1、 Jha, Abadh Kishor,Jain, Nidhi. "The microwave-assisted ortho-alkylation of azine N-oxides with N-tosylhydrazones catalyzed by copper(i) iodide". . p. 1831 - 1834. Retrieved 2016/02/05.
• 2、 -. "Oxaboroles and salts thereof, and their use as biocides". . . Retrieved 2008/06/13.