Acetamide, N-[4-(ethenyloxy)phenyl]-

Base Information

• Chemical Name: Acetamide, N-[4-(ethenyloxy)phenyl]-
• CAS No.: 830-04-6
• Molecular Formula: C10H11NO2
• Molecular Weight: 177.203
• DSSTox Substance ID: DTXSID00466086
• Nikkaji Number: J1.720.251K
• Wikidata: Q82292499
• Mol file: 830-04-6.mol

Synonyms:830-04-6;Acetamide, N-[4-(ethenyloxy)phenyl]-;DTXSID00466086;N-(4-(Vinyloxy)phenyl)acetamide;AKOS015712396

Chemical Property of Acetamide, N-[4-(ethenyloxy)phenyl]-

Chemical Property:

• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 177.078978594
• Heavy Atom Count: 13
• Complexity: 183

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=CC=C(C=C1)OC=C

Technology Process of Acetamide, N-[4-(ethenyloxy)phenyl]-

There total 6 articles about Acetamide, N-[4-(ethenyloxy)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-acetaminophenol (103-90-2,8055-08-1) + tetravinyltin (IV) (1112-56-7) → N-[4-(vinyloxy)-phenyl]-acetamide (830-04-6)

Guidance literature:

With copper diacetate; oxygen; In acetonitrile; at 20 ℃; for 22h;

DOI:10.1021/jo016037z

Reference yield: 92.0%

ethene (74-85-1) + 4-acetaminophenol (103-90-2,8055-08-1) → N-[4-(vinyloxy)-phenyl]-acetamide (830-04-6)

Guidance literature:

ethene; With polystyrene-bound selenenyl bromide; In tetrahydrofuran; at 20 ℃; for 0.0833333h;

4-acetaminophenol; With tetra-(n-butyl)ammonium iodide; potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 20 ℃; for 10h;

With dihydrogen peroxide; In tetrahydrofuran; at 20 ℃; for 0.5h;

DOI:10.1055/s-2004-834874

Reference yield: 79.0%

vinyl acetate (108-05-4,9003-20-7) + 4-acetaminophenol (103-90-2,8055-08-1) → N-[4-(vinyloxy)-phenyl]-acetamide (830-04-6)

Guidance literature:

With bis(1,5-cyclooctadiene)diiridium(I) dichloride; sodium carbonate; In toluene; at 100 ℃; for 15h; Inert atmosphere;

DOI:10.15227/orgsyn.082.0055

upstream raw materials:

4-acetaminophenol

tetravinyltin (IV)

ethene

vinyl acetate

Downstream raw materials:

N-[2-(4-Phenylazo-phenylazo)-4-vinyloxy-phenyl]-acetamide

Refernces

• 1、 Fu, Gui-Yun,Yu, La-Mei,Mao, Xue-Chun,Wu, Dan. "β-Phenylselenoethanol, an efficient reagent for the one-pot synthesis of aryl vinyl ethers". experimental part. p. 595 - 597. Retrieved 2009/10/15.
• 2、 Sheng, Shou-Ri,Liu, Xiao-Ling,Wang, Xing-Cong,Xin, Qin,Song, Cai-Sheng. "Polymer-supported β-bromoethyl selenide: An efficient reagent for the synthesis of aryl vinyl ethers". . p. 2833 - 2836. Retrieved 2007/10/03.