3,6-BIS(2-HYDROXYETHYL)-2,5-DIKETOPIPERAZINE

Base Information

• Chemical Name: 3,6-BIS(2-HYDROXYETHYL)-2,5-DIKETOPIPERAZINE
• CAS No.: 50975-79-6
• Molecular Formula: C8H14N2O4
• Molecular Weight: 202.21
• Hs Code.: 2933599090
• Mol file: 50975-79-6.mol

Synonyms:3,6-Bis(2-hydroxyethyl)-2,5-piperazinedione;3,6-Bis(2-hydroxyethyl)-2,5-diketopiperazine;3,6-bis-(2-Hydroxyethyl)-2,5-diketopiperazine (racemic mixture);3,6-Bis(2-hydroxyethyl)-2,5-diketopiperazine, 98 %;

Chemical Property of 3,6-BIS(2-HYDROXYETHYL)-2,5-DIKETOPIPERAZINE

Chemical Property:

• Appearance/Colour: White crystals or crystalline powder
• Vapor Pressure: 1.08E-17mmHg at 25°C
• Melting Point: 188 °C
• Refractive Index: 1.494
• Boiling Point: 614.9 °C at 760 mmHg
• Flash Point: 325.7 °C
• PSA: 98.66000
• Density: 1.25 g/cm³
• LogP: -1.60800

Purity/Quality:

99% ^*data from raw suppliers

3,6-BIS(2-HYDROXYETHYL)-2,5-DIKETOPIPERAZINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,6-BIS(2-HYDROXYETHYL)-2,5-DIKETOPIPERAZINE

There total 5 articles about 3,6-BIS(2-HYDROXYETHYL)-2,5-DIKETOPIPERAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

L-homoserine (672-15-1,119736-88-8) → (S)-cis-3,6-bis-(2-hydroxy-ethyl)-piperazine-2,5-dione (28814-72-4,46318-21-2,50975-79-6)

Guidance literature:

In ethylene glycol; at 150 ℃; for 36h;

Reference yield:

2-phenylhydrazono-γ-butyrolactone (24186-16-1) + ethanol (64-17-5) → aniline (62-53-3) + 3,6-bis-(β-hydroxyethyl)-2,5-diketopiperazine (50975-79-6)

Guidance literature:

at 100 - 150 ℃; under 88260.9 Torr; Hydrogenation;

DOI:10.1021/ja01261a022

Reference yield:

→ DL-Homoserine (1927-25-9,119736-88-8) + 3,6-bis-(β-hydroxyethyl)-2,5-diketopiperazine (50975-79-6)

Guidance literature:

With sodium hydrogencarbonate; optically inactive 3,6-bis-<2-hydroxy-ethyl>-piperazine-2,5-dione of mp: 202 degree;

DOI:10.1021/ja01178a037

upstream raw materials:

2-phenylhydrazono-γ-butyrolactone

ethanol

L-homoserine

Downstream raw materials:

3,6-bis-(β-chloroethyl)-2,5-diketopiperazine

Refernces

• 1、 -. "Method for preparing L-glufosinate-ammonium". Paragraph 0030-0035. . Retrieved 2020/09/23.