Georgywood

Base Information

• Chemical Name: Georgywood
• CAS No.: 185429-83-8
• Molecular Formula: C₁₆H₂₆O
• Molecular Weight: 234.382
• Mol file: 185429-83-8.mol

Synonyms:Ethanone,1-(1,2,3,4,5,6,7,8-octahydro-1,2,8,8-tetramethyl-2-naphthalenyl)-, cis-;Georgywood; b-Georgywood

Chemical Property of Georgywood

Chemical Property:

• Vapor Pressure: 0.000538mmHg at 25°C
• Boiling Point: 312.2°C at 760 mmHg
• Flash Point: 127.7°C
• PSA: 17.07000
• Density: 0.95g/cm³
• LogP: 4.51830

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Georgywood

There total 24 articles about Georgywood which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

(-)-(1S,2R)-1-[1,2-dimethyl-4-(4-methyl-pent-3-enyl)-cyclohex-3-enyl]-ethanone (828933-33-1) → (-)-(1R,2S)-1-(1,2,8,8-tetramethyl-1,2,3,4,5,6,7,8-octahydro-naphthalen-2-yl)-ethanone (185429-83-8)

Guidance literature:

With methylaluminum dichloride; In hexane; toluene; at 65 ℃; for 4h;

DOI:10.1021/ja057483x

Reference yield: 82.5%

cis-1-[1,2-dimethyl-4-(4-methylpent-3-enyl)cyclohex-3-enyl]ethanone → cis-2-acetyl-1,2,3,4,5,6,7,8-octahydro-1,2,8,8-tetramethylnaphthalene (185429-83-8)

Guidance literature:

With aluminum (III) chloride; methylaluminum sesquiiodide; methylene chloride; aluminium; methyl iodide; at 25 - 120 ℃; for 3h; under 760.051 Torr;

cis-1-[1,2-dimethyl-4-(4-methylpent-3-enyl)cyclohex-3-enyl]ethanone; In toluene; at 10 - 70 ℃; for 2 - 3h;

Reference yield: 60.0%

methyl iodide (74-88-4) + 1-(1,2,3,4,5,6,7,8-octahydro-1,8,8-trimethylnaphthalen-2-yl)ethan-1-one → georgywood (185429-83-8)

Guidance literature:

With sodium hydride; In tetrahydrofuran; for 48h; Heating;

DOI:10.1016/j.tet.2004.04.007

upstream raw materials:

methyl iodide

(E)-7-deuterio-2-methyl-6-methylene-nona-2,7-diene

(E)-3-deuterio-4,8-dimethylnona-2,7-dien-4-ol

4,8-Dimethyl-non-7-en-2-yn-4-ol

Refernces

• 1、 Turner, Keith. "Erratum: A review of U.S. patents in the field of organic process development published during august and september 2009 (Organic Process Research and Development (2010) 14 (8-18))". . p. 481 - 481. Retrieved 2010.
• 2、 Borosy, Andras,Frater, Georg,Müller, Urs,Schr?der, Fridtjof. "Endo-selective Diels-Alder reaction of methacrylonitrile: application to the synthesis of Georgywood". experimental part. p. 10495 - 10505. Retrieved 2010/02/28.