4,4,5-Trifluoro-2,5-bis(trifluoromethyl)-1,3-dioxolane-2-carbonyl fluoride

Base Information

• Chemical Name: 4,4,5-Trifluoro-2,5-bis(trifluoromethyl)-1,3-dioxolane-2-carbonyl fluoride
• CAS No.: 7385-65-1
• Molecular Formula: C6F10 O3
• Molecular Weight: 310.048
• Hs Code.: 2932999099
• European Community (EC) Number: 230-965-5
• DSSTox Substance ID: DTXSID70884379
• Nikkaji Number: J278.799G
• Mol file: 7385-65-1.mol

Synonyms:7385-65-1;4,4,5-Trifluoro-2,5-bis(trifluoromethyl)-1,3-dioxolane-2-carbonyl fluoride;EINECS 230-965-5;1,3-Dioxolane-2-carbonyl fluoride, 4,4,5-trifluoro-2,5-bis(trifluoromethyl)-;SCHEMBL8998716;DTXSID70884379;perfluoro-2,4-dimethyl-2-fluorocarbonyl-1,3-dioxolane;4,4,5-Trifluoro-2,5-bis(trifluoromethyl)- 1,3-Dioxolane-2-carbonyl fluoride

Chemical Property of 4,4,5-Trifluoro-2,5-bis(trifluoromethyl)-1,3-dioxolane-2-carbonyl fluoride

Chemical Property:

• Vapor Pressure: 20.5mmHg at 25°C
• Boiling Point: 113.8°C at 760 mmHg
• Flash Point: 23°C
• PSA: 35.53000
• Density: 1.79g/cm³
• LogP: 2.60880
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 1
• Exact Mass: 309.96877548
• Heavy Atom Count: 19
• Complexity: 399

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(=O)(C1(OC(C(O1)(F)F)(C(F)(F)F)F)C(F)(F)F)F

Technology Process of 4,4,5-Trifluoro-2,5-bis(trifluoromethyl)-1,3-dioxolane-2-carbonyl fluoride

There total 7 articles about 4,4,5-Trifluoro-2,5-bis(trifluoromethyl)-1,3-dioxolane-2-carbonyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

→ perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid sodium salt + perfluoro-2,4-dimethyl-2-fluorocarbonyl-1,3-dioxolane (7385-65-1)

Guidance literature:

With sodium carbonate;

Reference yield: 68.0%

Hexafluoropropene oxide (428-59-1,25038-02-2) + 4-fluoro-5-oxo-2,4-bis(trifluoromethyl)-1,3-dioxolane-2-carbonyl fluoride (7345-49-5) → perfluoro-2,4-dimethyl-2-fluorocarbonyl-1,3-dioxolane (7385-65-1)

Guidance literature:

With cesium fluoride; In diethylene glycol dimethyl ether; at 0 - 120 ℃; for 26h; under 60006 Torr; Autoclave; Cooling with ice;

Reference yield: 68.0%

4-fluoro-5-oxo-2,4-bis(trifluoromethyl)-1,3-dioxolane-2-carbonyl fluoride (7345-49-5) → perfluoro-2,4-dimethyl-2-fluorocarbonyl-1,3-dioxolane (7385-65-1)

Guidance literature:

With Hexafluoropropene oxide; cesium fluoride; In diethylene glycol dimethyl ether; at 0 - 120 ℃; for 26h; Autoclave; Large scale;

upstream raw materials:

α,α,α-trifluorotoluene

Hexafluoropropene oxide

4-fluoro-5-oxo-2,4-bis(trifluoromethyl)-1,3-dioxolane-2-carbonyl fluoride

perfluoro-2-oxo-3,6-dimethyl-1,4-dioxane

Downstream raw materials:

2-hydro-perfluoro(2,4-dimethyl-1,3-dioxolane)

2-(difluoromethylene)-4,4,5-trifluoro-5-(trifluoromethyl)-1,3-dioxolane

1,2-bis(perfluoro-2-hydro-4-methyl-1,3-dioxolan-2-ylmethoxy)benzene

perfluoromethyl (2,4-dimethyl-1,3-dioxolan-2-yl) ketone N-methyl-N-phenylhydrazone

Refernces

• 1、 -. "FLUOROLACTONE AND METHOD FOR PRODUCING SAME". Paragraph 0291-0294. . Retrieved 2021/12/03.
• 2、 -. "METHOD FOR PRODUCING PERFLUORO (2,4-DIMETHYL-2-FLUOROFORMYL-1,3-DIOXOLANE)". Paragraph 0046-0065. . Retrieved 2020/12/15.