Technology Process of Pentanedioic acid, 3-(phenylmethoxy)-, diethyl ester
There total 4 articles about Pentanedioic acid, 3-(phenylmethoxy)-, diethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
diethyl 3-hydroxyglutarate; benzaldehyde;
With
Hexamethyldisiloxane; trimethylsilyl trifluoromethanesulfonate;
In
tetrahydrofuran;
at -30 ℃;
for 2h;
Inert atmosphere;
With
triethylsilane;
In
tetrahydrofuran;
at -30 ℃;
for 16h;
Inert atmosphere;
With
sodium tetrahydroborate;
In
methanol;
at 0 ℃;
for 1h;
Inert atmosphere;
DOI:10.1021/ol402887z
- Guidance literature:
-
With
trifluorormethanesulfonic acid;
In
dichloromethane; cyclohexane;
at 0 ℃;
for 24h;
DOI:10.1021/jo402829b
- Guidance literature:
-
diethyl 3-<(trimethylsilyl)oxy>pentanedioate;
With
triethylsilane; iron(III) chloride;
In
acetone;
for 0.25h;
Inert atmosphere;
benzaldehyde;
In
acetone;
Reagent/catalyst;
Inert atmosphere;
DOI:10.1002/ejoc.201301374
