4-Sulfanyl-L-phenylalanine

Base Information

• Chemical Name: 4-Sulfanyl-L-phenylalanine
• CAS No.: 84053-10-1
• Molecular Formula: C9H11NO2S
• Molecular Weight: 197.258
• DSSTox Substance ID: DTXSID10570289
• Nikkaji Number: J713.187I
• Wikidata: Q82457679
• Mol file: 84053-10-1.mol

Synonyms:4-Sulfanyl-L-phenylalanine;p-mercaptophenylalanine;84053-10-1;SCHEMBL1595553;DTXSID10570289

Chemical Property of 4-Sulfanyl-L-phenylalanine

Chemical Property:

• XLogP3: -1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 197.05104977
• Heavy Atom Count: 13
• Complexity: 179

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1CC(C(=O)O)N)S
• Isomeric SMILES: C1=CC(=CC=C1C[C@@H](C(=O)O)N)S

Technology Process of 4-Sulfanyl-L-phenylalanine

There total 7 articles about 4-Sulfanyl-L-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

amoxycillin trihydrate (26889-93-0,81030-75-3) → amoxicillin (2R)-piperazine-2',5'-dione (94659-47-9) + amoxicillin (2S)-piperazine-2',5'-dione (94659-47-9)

Guidance literature:

In various solvent(s); for 20h; Ambient temperature; pH=9.2;

DOI:10.1248/cpb.34.2239

Reference yield:

2-amino-3-(4-mercaptophenyl)propanoic acid (84053-11-2) → 4-mercapto-phenylalanine (84053-10-1)

Guidance literature:

With hydrogenchloride; tin;

Reference yield:

→ 5,10,15,20-tetrakis(2-pyridyl)porphyrin (40904-90-3)

Guidance literature:

aus 2-Formylpyridin und Pyrrol;

DOI:10.1248/cpb.25.884

upstream raw materials:

2-amino-3-(4-mercaptophenyl)propanoic acid

amoxicillin (2R)-piperazine-2',5'-dione

amoxycillin trihydrate

L-phenylalanine

Downstream raw materials:

(L-phenylalanyl) p-tolyl disulfide

(S)-S-(4-methylbenzyl)-4'-mercaptophenylalanine

1,(4'-SH)Phe⁴>AT

L-S-(acetamidomethyl)-N^α-t-butoxycarbonyl-4'-mercaptophenylalanine

Refernces

• 1、 Haginaka,Wakai. "Epimerization of amoxicillin piperazine-2,5-dione in acidic solutions". . p. 2239 - 2242. Retrieved 2007/10/02.
• 2、 Sugata,Yamanouchi,Matsushima. "Meso tetrapyridylporphins and their metal complexes. Syntheses and physico chemical properties". . p. 884 - 889. Retrieved 2007/10/05.