Technology Process of 5-Allyloxy-4-chloro-2-fluoroaniline
There total 1 articles about 5-Allyloxy-4-chloro-2-fluoroaniline which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
3-aminopyrazinoic acid;
With
N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.833333h;
2-chloro-4-fluoro-5-aminophenyl allyl ether;
With
dmap; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 4h;
With
acetic anhydride; orthoformic acid triethyl ester;
at 170 ℃;
for 2h;
- Guidance literature:
-
4-amino-pyrimidin-5-carboxylic acid;
With
HATU;
In
N,N-dimethyl-formamide;
at 50 ℃;
for 1h;
2-chloro-4-fluoro-5-aminophenyl allyl ether;
With
dmap; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
at 60 ℃;
for 32h;