6-AZIDO-6-DEOXY-D-GALACTOSE

Base Information

• Chemical Name: 6-AZIDO-6-DEOXY-D-GALACTOSE
• CAS No.: 20847-05-6
• Molecular Formula: C6H11 N3 O5
• Molecular Weight: 205.17
• Hs Code.: 2940000080
• Mol file: 20847-05-6.mol

Synonyms:6-Azido-6-deoxy-D-glucose

Chemical Property of 6-AZIDO-6-DEOXY-D-GALACTOSE

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 147.74000
• Density: g/cm³
• LogP: -2.60804
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

6-Azido-6-deoxy-D-galactose ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: 6-Azido-6-deoxy-D-galactose is a new selective metabolic chemical reporter (MCR) for labeling O-?GlcNAc-?modified proteins in cells.

Technology Process of 6-AZIDO-6-DEOXY-D-GALACTOSE

There total 15 articles about 6-AZIDO-6-DEOXY-D-GALACTOSE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,5-di-O-acetyl-6-deoxy-1,2-O-isopropylidene-6-azido-α-D-glucofuranose (65371-16-6) → 6-Azido-6-desoxy-D-glucopyranose (20847-05-6,138332-00-0,138332-01-1)

Guidance literature:

With trifluoroacetic acid; In water; at 20 ℃; for 1h;

Reference yield: 70.0%

6-bromo-6-deoxy-D-glucopyranose (18981-83-4,28528-87-2) → 6-Azido-6-desoxy-D-glucopyranose (20847-05-6,138332-00-0,138332-01-1)

Guidance literature:

With lithium azide; In water; N,N-dimethyl-formamide; at 80 ℃; for 1h;

DOI:10.1016/j.tetasy.2006.04.018

Reference yield: 64.0%

6,6'-diazido-6,6'-dideoxysucrose (33585-16-9) → 6-azido-6-deoxy-D-fructofuranose + 6-Azido-6-desoxy-D-glucopyranose (20847-05-6,138332-00-0,138332-01-1)

Guidance literature:

With Amberlite IR 120; In water; at 40 ℃;

DOI:10.1016/0040-4039(92)88046-8

upstream raw materials:

6,6'-diazido-6,6'-dideoxysucrose

3,5-di-O-acetyl-6-deoxy-1,2-O-isopropylidene-6-azido-α-D-glucofuranose

β-6-Azido-6-deoxy-D-fructose

6-bromo-6-deoxy-D-glucopyranose

Downstream raw materials:

6-Amino-6-deoxy-D-glucose hydrochloride

1-deoxymannojirimycin

1,6-dideoxy-1,6-imino-(2S,3R,4R,5R)-D-glucitol

6-Azido-6-desoxy-1,2:3,5-di-O-isopropyliden-α-D-glucofuranose

Refernces

• 1、 Miyazawa, Tomoyuki,Abe, Haruka,Suzuki, Takayuki,Togashi, Yosuke,Koshiji, Kazuhiro,Nonaka, Yuki,Hasegawa, Teruaki. "Curdlan as a polymeric starting material to access C6-modified glucose derivatives". . p. 252 - 266. Retrieved 2014/07/07.
• 2、 -. "Novel drug delivery compositions". Page/Page column 13. . Retrieved 2010/11/25.