SQ 26654

Base Information

• Chemical Name: SQ 26654
• CAS No.: 85798-89-6
• Molecular Formula: C₂₁H₃₄O₄
• Molecular Weight: 350.499
• Mol file: 85798-89-6.mol

Synonyms:(Z)-7-[(1S,2S,3S,4R)-3-((E)-(R)-3-Hydroxy-oct-1-enyl)-7-oxa-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid;

Chemical Property of SQ 26654

Chemical Property:

• PSA: 66.76000
• LogP: 4.47860

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of SQ 26654

There total 8 articles about SQ 26654 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-7-{(1R,2S,4S)-3-[(E)-3-(Tetrahydro-pyran-2-yloxy)-oct-1-enyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid (78845-46-2,78919-08-1,82337-13-1,82337-45-9) → (Z)-7-[(1R,2S,4S)-3-((E)-(R)-3-Hydroxy-oct-1-enyl)-7-oxa-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid (70120-38-6,70144-99-9,71242-22-3,74868-29-4,74868-30-7,74868-31-8,74868-32-9,74868-33-0,74868-34-1,74868-35-2,74892-31-2,79703-23-4,79703-24-5,82337-14-2,82337-44-8,82468-59-5,85798-85-2,85798-86-3,85798-87-4,85798-88-5,85798-89-6,85798-90-9,85798-91-0,85798-92-1,85798-93-2,85798-94-3) + (Z)-7-[(1R,2S,4S)-3-((E)-(S)-3-Hydroxy-oct-1-enyl)-7-oxa-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid (70120-38-6,70144-99-9,71242-22-3,74868-29-4,74868-30-7,74868-31-8,74868-32-9,74868-33-0,74868-34-1,74868-35-2,74892-31-2,79703-23-4,79703-24-5,82337-14-2,82337-44-8,82468-59-5,85798-85-2,85798-86-3,85798-87-4,85798-88-5,85798-89-6,85798-90-9,85798-91-0,85798-92-1,85798-93-2,85798-94-3)

Guidance literature:

With acetic acid; In tetrahydrofuran; water; at 40 ℃;

Reference yield:

(Z)-7-{(1R,2S,4S)-3-[(E)-3-(Tetrahydro-pyran-2-yloxy)-oct-1-enyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid (78845-46-2,78919-08-1,82337-13-1,82337-45-9) → (Z)-7-[(1R,2S,4S)-3-((E)-(R)-3-Hydroxy-oct-1-enyl)-7-oxa-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid (70120-38-6,70144-99-9,71242-22-3,74868-29-4,74868-30-7,74868-31-8,74868-32-9,74868-33-0,74868-34-1,74868-35-2,74892-31-2,79703-23-4,79703-24-5,82337-14-2,82337-44-8,82468-59-5,85798-85-2,85798-86-3,85798-87-4,85798-88-5,85798-89-6,85798-90-9,85798-91-0,85798-92-1,85798-93-2,85798-94-3) + (Z)-7-[(1R,2S,4S)-3-((E)-(S)-3-Hydroxy-oct-1-enyl)-7-oxa-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid (70120-38-6,70144-99-9,71242-22-3,74868-29-4,74868-30-7,74868-31-8,74868-32-9,74868-33-0,74868-34-1,74868-35-2,74892-31-2,79703-23-4,79703-24-5,82337-14-2,82337-44-8,82468-59-5,85798-85-2,85798-86-3,85798-87-4,85798-88-5,85798-89-6,85798-90-9,85798-91-0,85798-92-1,85798-93-2,85798-94-3)

Guidance literature:

With acetic acid; In tetrahydrofuran; water; at 40 ℃;

Reference yield:

(4-carboxybutylene)triphenylphosphorane (39968-97-3) → (Z)-7-[(1R,2S,4S)-3-((E)-(R)-3-Hydroxy-oct-1-enyl)-7-oxa-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid (70120-38-6,70144-99-9,71242-22-3,74868-29-4,74868-30-7,74868-31-8,74868-32-9,74868-33-0,74868-34-1,74868-35-2,74892-31-2,79703-23-4,79703-24-5,82337-14-2,82337-44-8,82468-59-5,85798-85-2,85798-86-3,85798-87-4,85798-88-5,85798-89-6,85798-90-9,85798-91-0,85798-92-1,85798-93-2,85798-94-3)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethylsulfoxide

2: acetic acid / H₂O; tetrahydrofuran / 40 °C

With acetic acid; In tetrahydrofuran; water; dimethyl sulfoxide;

upstream raw materials:

(Z)-7-{(1R,2S,4S)-3-[(E)-3-(Tetrahydro-pyran-2-yloxy)-oct-1-enyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid

(4-carboxybutylene)triphenylphosphorane

{(1R,2S,4S)-3-[(E)-3-(Tetrahydro-pyran-2-yloxy)-oct-1-enyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-acetaldehyde

{(1R,2S,4S)-3-[(E)-3-(Tetrahydro-pyran-2-yloxy)-oct-1-enyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-acetonitrile

Refernces