1,2,5-TRIPHENYLPYRROLE

Base Information

• Chemical Name: 1,2,5-TRIPHENYLPYRROLE
• CAS No.: 851-33-2
• Molecular Formula: C22H17N
• Molecular Weight: 295.384
• Hs Code.: 2933990090
• Mol file: 851-33-2.mol

Synonyms:1-phenyl-2,5-diphenylpyrrole;Pyrrole,1,2,5-triphenyl;1,2,5-Triphenyl-pyrrol;1H-Pyrrole,1,2,5-triphenyl;1,2,5-Triphenyl-1H-pyrrole;1,2,5-triphenyl-pyrrole;N-phenyl-2,5-diphenylpyrrole;

Chemical Property of 1,2,5-TRIPHENYLPYRROLE

Chemical Property:

• PSA: 4.93000
• LogP: 5.81130

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2,5-TRIPHENYLPYRROLE

There total 35 articles about 1,2,5-TRIPHENYLPYRROLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

aniline (62-53-3) + phenacylacetophenone (495-71-6) → 1,2,5-triphenyl-1H-pyrrole (851-33-2)

Guidance literature:

In acetic acid; for 2h; Heating;

DOI:10.1039/a704065b

Reference yield: 96.0%

1,4-diphenyl-1,3-butadiyne (886-66-8) + aniline (62-53-3) → 1,2,5-triphenyl-1H-pyrrole (851-33-2)

Guidance literature:

With copper(l) chloride; at 100 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tetlet.2010.06.092

Reference yield: 90.0%

N-(1-phenylethylidene)aniline (1749-19-5) → 1,2,5-triphenyl-1H-pyrrole (851-33-2)

Guidance literature:

With titanium tetrachloride; triethylamine; In dichloromethane; at 0 - 25 ℃;

DOI:10.1021/jo982342h

upstream raw materials:

aniline hydrochloride

aniline

phenacylacetophenone

(N-benzoyl-anilino)-phenyl-acetonitrile

Downstream raw materials:

5-benzoyl-3-phenylisothiazole

triethylphenylsilane

1,1',2,2',5,5'-hexaphenyl-1H,1'H-3,3'-bipyrrole

3,4-Dibromo-1,2,5-triphenyl-1H-pyrrole

Refernces

• 1、 Ryabchuk, Pavel,Leischner, Thomas,Kreyenschulte, Carsten,Spannenberg, Anke,Junge, Kathrin,Beller, Matthias. "Cascade Synthesis of Pyrroles from Nitroarenes with Benign Reductants Using a Heterogeneous Cobalt Catalyst". supporting information. p. 18679 - 18685. Retrieved 2020/09/02.
• 2、 Younis, Fadi M.,Krieck, Sven,G?rls, Helmar,Westerhausen, Matthias. "s-Block-Metal-Mediated Hydroamination of Diphenylbutadiyne with Primary Arylamines Using a Dipotassium Tetrakis(amino)calciate Precatalyst". supporting information. p. 3577 - 3585. Retrieved 2015/08/06.