2-(2-Naphthyloxy)acetamide

Base Information

• Chemical Name: 2-(2-Naphthyloxy)acetamide
• CAS No.: 35368-77-5
• Molecular Formula: C12H11NO2
• Molecular Weight: 201.225
• Hs Code.: 2924299090
• European Community (EC) Number: 252-531-4
• UNII: XB5A873G2N
• DSSTox Substance ID: DTXSID20188859
• Nikkaji Number: J260.600C
• Wikidata: Q83060717
• Mol file: 35368-77-5.mol

Synonyms:2-(2-Naphthyloxy)acetamide;35368-77-5;2-(naphthalen-2-yloxy)acetamide;2-naphthalen-2-yloxyacetamide;2-naphthyloxyacetamide;XB5A873G2N;Acetamide, 2-(2-naphthalenyloxy)-;EINECS 252-531-4;AI3-26426;ss-Naphthoxyacetamid;UNII-XB5A873G2N;(2-Naphthalenyloxy)acetamide;2-(2-Naphthyloxy)ethanamide;SCHEMBL1478177;DTXSID20188859;MFCD00245699;AKOS008909118;MS-7225;SB77793;ACETAMIDE, 2-(2-NAPHTHYLOXY)-;CS-0306630;Z19834621

Chemical Property of 2-(2-Naphthyloxy)acetamide

Chemical Property:

• Vapor Pressure: 4.53E-08mmHg at 25°C
• Boiling Point: 443.7°Cat760mmHg
• PKA: 15.33±0.40(Predicted)
• Flash Point: 255.2°C
• PSA: 53.31000
• Density: 1.22g/cm³
• LogP: 2.85360
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 201.078978594
• Heavy Atom Count: 15
• Complexity: 230

Purity/Quality:

98%Min ^*data from raw suppliers

2-(2-NAPHTHYLOXY)ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C2C=C(C=CC2=C1)OCC(=O)N

Technology Process of 2-(2-Naphthyloxy)acetamide

There total 5 articles about 2-(2-Naphthyloxy)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

β-naphthol (135-19-3) + Chloroacetamide (79-07-2) → 2-naphthalen-2-yloxy-acetamide (35368-77-5)

Guidance literature:

With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 20 ℃; for 5h;

DOI:10.3390/molecules191118620

Reference yield:

(2-naphthoyl)oxyacetic acid (120-23-0) → 2-naphthalen-2-yloxy-acetamide (35368-77-5)

Guidance literature:

With thionyl chloride; anschliessendes Behandeln mit wss. NH₃;

Reference yield:

ethyl (naphthalen-2-yloxy)acetate (6036-14-2) → 2-naphthalen-2-yloxy-acetamide (35368-77-5)

Guidance literature:

With ammonium hydroxide;

upstream raw materials:

(2-naphthoyl)oxyacetic acid

ethyl (naphthalen-2-yloxy)acetate

Chloroacetamide

β-naphthol

Refernces