2-Amino-4,6-dichlorophenol

Base Information

• Chemical Name: 2-Amino-4,6-dichlorophenol
• CAS No.: 527-62-8
• Molecular Formula: C6H5 Cl2 N O
• Molecular Weight: 178.018
• Hs Code.: 2922299090
• European Community (EC) Number: 208-421-3
• NSC Number: 658464
• UN Number: 2811
• UNII: ES86DYT9KH
• DSSTox Substance ID: DTXSID00870583
• Nikkaji Number: J7.742I
• Wikidata: Q27277335
• Mol file: 527-62-8.mol

Synonyms:2-amino-4,6-dichlorophenol

Chemical Property of 2-Amino-4,6-dichlorophenol

Chemical Property:

• Appearance/Colour: light yellow or white solid
• Vapor Pressure: 0.00153mmHg at 25°C
• Melting Point: 97 ºC
• Refractive Index: 1.5680 (estimate)
• Boiling Point: 286.5 °C at 760 mmHg
• PKA: 7.85±0.23(Predicted)
• Flash Point: 127.1 °C
• PSA: 46.25000
• Density: 1.56 g/cm³
• LogP: 2.86240
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 176.9748192
• Heavy Atom Count: 10
• Complexity: 122
• Transport DOT Label: Poison

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-4,6-dichlorophenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1N)O)Cl)Cl
• Uses: 2-Amino-4,6-dichlorophenol is used in preparation of novel heteroaryl-substituted Aminoalkyl Azole compounds as pesticides.

Technology Process of 2-Amino-4,6-dichlorophenol

There total 10 articles about 2-Amino-4,6-dichlorophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2,4-dichloro-6-nitrophenol (609-89-2) → 2,4-dichloro-6-aminophenol (527-62-8)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol; at 20 ℃; for 96h; under 750.06 Torr;

Reference yield: 80.0%

2,4-dichloro-6-nitrophenol (609-89-2) + stannous chloride (7772-99-8) → 2,4-dichloro-6-aminophenol (527-62-8)

Guidance literature:

In ethanol;

Reference yield:

sodium dithionate + 2,4-dichloro-6-nitrophenol (609-89-2) → 2,4-dichloro-6-aminophenol (527-62-8)

Guidance literature:

In water; sodium hydrogencarbonate;

upstream raw materials:

2,4-dichloro-6-nitrophenol

trans-2,4-dichloro-6-phenylazo-phenol

hydrogenchloride

4,6,4',6'-tetrachloro-2,2'-azo-di-phenol

Downstream raw materials:

5,7-dichloro-2-chloromethyl-benzooxazole

2-(3,5-dichloro-2-hydroxyanilino)-1,4-naphthoquinone-3-pyridinium chloride

N-(3,5-Dichloro-2-hydroxy-phenyl)-oxalamic Acid Ethyl Ester

cis-N₂-(4-{4-amino-1-[4-(4-methylpiperazino)cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}phenyl)-4-methyl-1,3-benzoxazol-2-amine

Refernces

• 1、 Yoshida, Satoshi,Watanabe, Takashi,Sato, Yasuo. "Regulatory molecules for the 5-HT3 receptor ion channel gating system". . p. 3515 - 3523. Retrieved 2008/02/07.
• 2、 -. "Oxamide inhibitors of plasminogen activator inhibitor-1". Page/Page column 12. . Retrieved 2010/02/11.