3,6-Ethano-3,4,5,6-tetrahydropyridazine

Base Information

• Chemical Name: 3,6-Ethano-3,4,5,6-tetrahydropyridazine
• CAS No.: 3310-62-1
• Molecular Formula: C6H10N2
• Molecular Weight: 110.159
• Hs Code.: 2933990090
• Mol file: 3310-62-1.mol

Synonyms:Fluorazophore-P;

Chemical Property of 3,6-Ethano-3,4,5,6-tetrahydropyridazine

Chemical Property:

• Vapor Pressure: 6.53mmHg at 25°C
• Melting Point: 141 °C
• Boiling Point: 144°Cat760mmHg
• Flash Point: 32°C
• PSA: 24.72000
• Density: 1.35g/cm³
• LogP: 0.63460

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Use Description: 3,6-Ethano-3,4,5,6-tetrahydropyridazine, a heterocyclic compound, serves various purposes across different fields. In the pharmaceutical industry, it is employed as a key intermediate in the synthesis of organic compounds with potential pharmaceutical applications, aiding in the development of novel drugs and therapeutic agents. In the field of organic chemistry, this compound is utilized as a versatile building block for the creation of more complex molecules, facilitating advancements in chemical research and materials science. Additionally, 3,6-Ethano-3,4,5,6-tetrahydropyridazine may have applications in the development of agrochemicals, contributing to the formulation of pesticides and herbicides used in agriculture for pest and weed management. Its adaptability and role in the synthesis of valuable compounds underscore its importance in various scientific and industrial endeavors.

Technology Process of 3,6-Ethano-3,4,5,6-tetrahydropyridazine

There total 15 articles about 3,6-Ethano-3,4,5,6-tetrahydropyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-Thia-2,6-diazatricyclo<5.2.2.0>undecane-3,5-dione (41316-20-5) → 2,3-diazabicyclo[2.2.2]oct-2-ene (3310-62-1)

Guidance literature:

In d⁽⁴⁾-methanol; for 0.25h; Ambient temperature; Irradiation;

DOI:10.1021/jo00092a013

Reference yield: 42.0%

di-isopropyl 2,3-diazabicyclo<2.2.2>octane-2,3-dicarboxylate (124497-53-6) → 2,3-diazabicyclo<2.2.2>oct-2-ene (3310-62-1)

Guidance literature:

With trimethylsilyl iodide; In chloroform; for 3h; Heating;

Reference yield:

4-thia-2,6-diazatricyclo[5.2.2.02,6]undec-8-ene-3,5-dione (41316-16-9) → 2,3-diazabicyclo[2.2.2]oct-2-ene (3310-62-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / H₂ / Pd/C / ethanol / 2 h / atmospheric pressure

2: 100 percent / hexane / UV-irradiation

With hydrogen; palladium on activated charcoal; In ethanol; hexane;

DOI:10.1021/ol9906965

upstream raw materials:

1,4-Diazobicyclo[2,2,2]octane

diethyl 2,3-diazabicyclo<2.2.2>oct-5-ene-2,3-dicarboxylate

4-Thia-2,6-diazatricyclo<5.2.2.0>undecane-3,5-dione

phosgene

Downstream raw materials:

1,4-Diazobicyclo[2,2,2]octane

2-Methyl-2,3-diazabicyclo<2.2.2>oct-2-enylium fluorosulfonate

2,8-diazatetracyclo<7.2.2.2^3,7.0^2,8>pentadeca-14-ene

2-tert-butyl-2,3-diazabicyclo<2.2.2>octane

Refernces

• 1、 Engel, Paul S.,Duan, Shaoming,Whitmire, Kenton H.. "Structure and Stability of an Azoalkane-Iodine Complex". . p. 5666 - 5667. Retrieved 1998.
• 2、 Nelsen, Stephen F.,Wang, Yichun. "Reactions of Bis(N,N'-bicyclic) Diazenium Dications". . p. 3082 - 3090. Retrieved 2007/10/02.