Methyl 1-aminocyclopentanecarboxylate hydrochloride

Base Information

• Chemical Name: Methyl 1-aminocyclopentanecarboxylate hydrochloride
• CAS No.: 60421-23-0
• Molecular Formula: C7H13 N O2 . Cl H
• Molecular Weight: 179.647
• Hs Code.: 2902190000
• European Community (EC) Number: 820-764-6
• DSSTox Substance ID: DTXSID70467828
• NSC Number: 161119
• Mol file: 60421-23-0.mol

Synonyms:60421-23-0;methyl 1-aminocyclopentanecarboxylate hydrochloride;Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride;Methyl 1-aminocyclopentane-1-carboxylate Hydrochloride;Methyl 1-amino-1-cyclopentanecarboxylate HCl;MFCD03840364;methyl 1-aminocyclopentane-1-carboxylate;hydrochloride;METHYL 1-AMINOCYCLOPENTYLCARBOXYLATE HCL;Cycloleucine Methyl Ester Hydrochloride;Methyl 1-amino-1-cyclopentanecarboxylate, HCl;methyl 1-aminocyclopen tanecarboxylate hydrochloride;1-Aminocyclopentanecarboxylic Acid Methyl Ester Hydrochloride;Cycloeucine methyl ester hydrochloride;Cyclopentanecarboxylic acid, 1-amino-, methyl ester, hydrochloride;SCHEMBL485571;DTXSID70467828;OPUJUITUYWGUEP-UHFFFAOYSA-N;1-amino-cyclopentanecarboxylic acid methyl ester hydrochloride;CS-B0437;NSC161119;AKOS015894247;AC-5711;GS-4490;NSC-161119;SY017501;A8433;AM20100472;FT-0649632;M2351;EN300-29590;methyl 1-aminocyclopentanecarboxylate HCl salt;methyl1-aminocyclopentanecarboxylatehydrochloride;methyl-1-aminocyclopentanecarboxylate hydrochloride;methyl-1-amino-1-cyclopentanoate hydrochloride salt;methyl-1-amino-1-cyclopentanecarboxylate hydrochloride;Cyclopentanecarboxylic acid, methyl ester, hydrochloride;F2147-0946;methyl 1-amino-cyclopentane-1-carboxylate hydrochloride;methyl-1-amino-1-cyclopentane carboxylate hydrochloride;Z235354625;Methyl 1-aminocyclopentanecarboxylate hydrochloride (1:1);Methyl 1-aminocyclopentane-1-carboxylate--hydrogen chloride (1/1)

Chemical Property of Methyl 1-aminocyclopentanecarboxylate hydrochloride

Chemical Property:

• Vapor Pressure: 0.653mmHg at 25°C
• Melting Point: 207-208 °C (decomp)
• Boiling Point: 186.7 °C at 760 mmHg
• Flash Point: 58.7 °C
• PSA: 52.32000
• Density: 1.081g/cm³
• LogP: 1.93320
• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 179.0713064
• Heavy Atom Count: 11
• Complexity: 139

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methyl 1-Aminocyclopentanecarboxylate Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1(CCCC1)N.Cl

Technology Process of Methyl 1-aminocyclopentanecarboxylate hydrochloride

There total 9 articles about Methyl 1-aminocyclopentanecarboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-amino-1-cyclopentanecarboxylic acid (52-52-8) → cycloleucine methyl ester hydrochloride (60421-23-0)

Guidance literature:

Reference yield: 100.0%

methanol (67-56-1) + 1-amino-1-cyclopentanecarboxylic acid (52-52-8) → cycloleucine methyl ester hydrochloride (60421-23-0)

Guidance literature:

With thionyl chloride; In methanol; at -15 - 20 ℃;

Reference yield: 94.0%

→ cycloleucine methyl ester hydrochloride (60421-23-0)

Guidance literature:

With thionyl chloride; at 0 - 20 ℃; for 16h;

upstream raw materials:

methanol

1-amino-1-cyclopentanecarboxylic acid

methyl 1-((tert-butoxycarbonyl)amino)cyclopentanecarboxylate

[1-(1-hydroxy-1-methylethyl)cyclopentyl]carbamic acid tert-butyl ester

Downstream raw materials:

7-Acetyl-9-(4-chloro-phenyl)-6,8,9-triaza-spiro[4.5]dec-7-en-10-one

7-Acetyl-9-p-tolyl-6,8,9-triaza-spiro[4.5]dec-7-en-10-one

N-(benzyloxycarbonyl)-β-benzyl-L-aspartyl-α-aminocyclopentanecarboxylic acid methyl ester

10-Oxo-9-p-tolyl-6,8,9-triaza-spiro[4.5]dec-7-ene-7-carboxylic acid methyl ester

Refernces

• 1、 Kim, Byoungmoo,Chinn, Alex J.,Fandrick, Daniel R.,Senanayake, Chris H.,Singer, Robert A.,Miller, Scott J.. "Distal Stereocontrol Using Guanidinylated Peptides as Multifunctional Ligands: Desymmetrization of Diarylmethanes via Ullman Cross-Coupling". supporting information. p. 7939 - 7945. Retrieved 2016/07/07.
• 2、 -. "A COMPOUND FOR INHIBITING 11B-HYDROXY STEROID DEHYDROGENASE 1, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME". Paragraph 0449-0451. . Retrieved 2014/08/06.