Technology Process of 1-Piperidinecarboxylic acid, 3,4-dihydroxy-4-phenyl-, phenylmethyl
ester
There total 7 articles about 1-Piperidinecarboxylic acid, 3,4-dihydroxy-4-phenyl-, phenylmethyl
ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-methyl-2-indolinone;
osmium(VIII) oxide;
In
tetrahydrofuran; water; tert-butyl alcohol;
for 2h;
Heating;
DOI:10.1016/j.tetlet.2005.10.015
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tetrahydrofuran / 2 h / -78 - 20 °C
2: BF3*Et2O / CH2Cl2 / 0.25 h / 20 °C
3: 84 percent / NMO / OsO4 / H2O; tetrahydrofuran; 2-methyl-propan-2-ol / 2 h / Heating
With
N-methyl-2-indolinone; boron trifluoride diethyl etherate;
osmium(VIII) oxide;
In
tetrahydrofuran; dichloromethane; water; tert-butyl alcohol;
DOI:10.1016/j.tetlet.2005.10.015
- Guidance literature:
-
Multi-step reaction with 5 steps
1: Et3N / CH2Cl2 / 1 h / 20 °C
2: Jones reagent / acetone / 0.25 h / at ice bath
3: tetrahydrofuran / 2 h / -78 - 20 °C
4: BF3*Et2O / CH2Cl2 / 0.25 h / 20 °C
5: 84 percent / NMO / OsO4 / H2O; tetrahydrofuran; 2-methyl-propan-2-ol / 2 h / Heating
With
N-methyl-2-indolinone; jones reagent; boron trifluoride diethyl etherate; triethylamine;
osmium(VIII) oxide;
In
tetrahydrofuran; dichloromethane; water; acetone; tert-butyl alcohol;
DOI:10.1016/j.tetlet.2005.10.015