Piperidine-1-sulfonamide

Base Information

• Chemical Name: Piperidine-1-sulfonamide
• CAS No.: 4108-90-1
• Molecular Formula: C5H12N2O2S
• Molecular Weight: 164.228
• Hs Code.: 2935009090
• NSC Number: 125083
• DSSTox Substance ID: DTXSID70298659
• Nikkaji Number: J807.999D
• Wikidata: Q27458351
• Pharos Ligand ID: ZCNPCRKHTCGN
• ChEMBL ID: CHEMBL169370
• Mol file: 4108-90-1.mol

Synonyms:piperidine-1-sulfonamide;1-Piperidinesulfonamide;4108-90-1;CHEMBL169370;piperdine sulfonamide;NSC125083;piperidine sulfonamide;piperidinosulfonylamine;SCHEMBL392889;piperidine-1-sulfonic acid amide;DTXSID70298659;AMY16317;BDBM50124176;MFCD11171675;AKOS009160750;BS-3897;NSC 125083;NSC-125083;SB42694;FT-0743241;EN300-41320;C91630;Q27458351;Z300095616;BE0

Chemical Property of Piperidine-1-sulfonamide

Chemical Property:

• Vapor Pressure: 0.00109mmHg at 25°C
• Refractive Index: 1.553
• Boiling Point: 300.8 °C at 760 mmHg
• Flash Point: 135.7 °C
• PSA: 71.78000
• Density: 1.33 g/cm³
• LogP: 1.39480
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 164.06194880
• Heavy Atom Count: 10
• Complexity: 188

Purity/Quality:

99% ^*data from raw suppliers

piperidine-1-sulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)S(=O)(=O)N

Technology Process of Piperidine-1-sulfonamide

There total 5 articles about Piperidine-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

→ piperidine-1-sulfonamide (4108-90-1)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; for 3h;

Reference yield: 63.0%

piperidine (110-89-4) → piperidine-1-sulfonamide (4108-90-1)

Guidance literature:

With N-(1-phenyl)sulfamide; at 106 ℃; for 12h;

DOI:10.1055/s-1983-30275

Reference yield:

piperidine (110-89-4) + 4-nitrophenyl sulfamate (108555-00-6) → piperidine-1-sulfonamide (4108-90-1) + 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0)

Guidance literature:

In acetonitrile; at 36.85 ℃; Further Variations:; Reaction partners; Kinetics;

DOI:10.1002/poc.1050

upstream raw materials:

piperidine

tert-butyl (piperidin-1-ylsulfonyl)carbamate

4-nitrophenyl sulfamate

Downstream raw materials:

piperidine-1-sulfonic acid [3-(4-chloro-phenyl)-4-phenyl-4,5-dihydro-pyrazole-1-carbothioyl]-amide

Piperidine-1-sulfonic acid 1-[3-(4-chloro-phenyl)-4-phenyl-4,5-dihydro-pyrazol-1-yl]-1-methylsulfanyl-meth-(Z)-ylideneamide

N-methyl-N-[(piperidin-1-yl)sulfonyl]-3-(4-chloropheny)-4-phenyl-4,5-dihydro-(1H)-pyrazole-1-carboxamidine

Phenyl[1-(piperidinosulfonylamino)ethyl]phenylphosphinate

Refernces

• 1、 -. "PYRAZOLE DERIVATIVES AND THEIR USE AS CANNABINOID RECEPTOR MEDIATORS". Page/Page column 40. . Retrieved 2015/11/27.
• 2、 -. "ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS". Page/Page column 109. . Retrieved 2015/01/09.