Lithium methoxy(phenylsulfanyl)(trimethylsilyl)methanide

Base Information

• Chemical Name: Lithium methoxy(phenylsulfanyl)(trimethylsilyl)methanide
• CAS No.: 87262-37-1
• Molecular Formula: C11H17LiOSSi
• Molecular Weight: 232.348
• DSSTox Substance ID: DTXSID90525555
• Mol file: 87262-37-1.mol

Synonyms:87262-37-1;Lithium methoxy(phenylsulfanyl)(trimethylsilyl)methanide;DTXSID90525555

Chemical Property of Lithium methoxy(phenylsulfanyl)(trimethylsilyl)methanide

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 232.09294130
• Heavy Atom Count: 15
• Complexity: 167

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: [Li+].CO[C-]([Si](C)(C)C)SC1=CC=CC=C1

Technology Process of Lithium methoxy(phenylsulfanyl)(trimethylsilyl)methanide

There total 1 articles about Lithium methoxy(phenylsulfanyl)(trimethylsilyl)methanide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trimethylsilane (88738-21-0) → lithium (87262-37-1)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at -80 ℃; for 1h;

DOI:10.1021/jo00171a045

Reference yield: 100.0%

lithium (87262-37-1) + benzaldehyde (100-52-7) → (E)-1-methoxy-2-phenyl-1-(phenylthio)ethene (88738-26-5)

Guidance literature:

In tetrahydrofuran; cyclohexane; Product distribution; Ambient temperature; other aldehydes and ketones, lithium;

DOI:10.1021/jo00356a025

Reference yield: 87.0%

lithium (87262-37-1) + 5β-Hydroxy-4aβ-methyl-8-methylene-3,4,4a,5,6,7,8,8aα-octahydronaphthalen-2(1H)-one (87262-36-0) → (1S,4aR,8aS)-6-[1-Methoxy-1-phenylsulfanyl-meth-(Z)-ylidene]-8a-methyl-4-methylene-decahydro-naphthalen-1-ol (87262-45-1,87262-46-2)

Guidance literature:

In tetrahydrofuran; 1) -80 degC, 1 h, 2) warm to room temp.;

DOI:10.1021/jo00171a045

upstream raw materials:

trimethylsilane

Downstream raw materials:

2-(methoxymethyl)-3-cyclopentanone

(Z)-7-[(1R,2R,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-(methoxy-phenylsulfanyl-trimethylsilanyl-methyl)-5-oxo-cyclopentyl]-hept-5-enoic acid methyl ester

(1S,4aR,8aS)-6-[1-Methoxy-1-phenylsulfanyl-meth-(Z)-ylidene]-8a-methyl-4-methylene-decahydro-naphthalen-1-ol

(4aR,8aS)-7-[1-Methoxy-1-phenylsulfanyl-meth-(Z)-ylidene]-4a-methyl-1-methylene-decahydro-naphthalene

Refernces