Ethyl2-cyano-3-ethyl-2-pentenoate

Base Information

• Chemical Name: Ethyl2-cyano-3-ethyl-2-pentenoate
• CAS No.: 868-04-2
• Molecular Formula: C10H15 N O2
• Molecular Weight: 181.235
• Mol file: 868-04-2.mol

Synonyms:Ethyl2-cyano-3,3-diethylacrylate; NSC 409975

Chemical Property of Ethyl2-cyano-3-ethyl-2-pentenoate

Chemical Property:

• Vapor Pressure: 0.00562mmHg at 25°C
• Boiling Point: 273.8°C at 760 mmHg
• Flash Point: 123.7°C
• PSA: 50.09000
• Density: 0.986g/cm³
• LogP: 2.18968

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl2-Cyano-3,3-diethylacrylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Ethyl 2-Cyano-3,3-diethylacrylate is a product of Knoevenagel condensation. Ethyl 2-Cyano-3,3-diethylacrylate can be synthesized to verify effectiveness of the silica catalysts for Knoevenagel condensation.

Technology Process of Ethyl2-cyano-3-ethyl-2-pentenoate

There total 2 articles about Ethyl2-cyano-3-ethyl-2-pentenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethyl 2-cyanoacetate (105-56-6) + pentan-3-one (96-22-0) → ethyl 2-cyano-3,3-diethylacrylate (868-04-2)

Guidance literature:

With 1-butyl-3-methylimidazolium hydroxide; at 25 - 30 ℃; for 2h;

DOI:10.1002/ejoc.200600335

Reference yield:

→ ethyl 2-cyano-3,3-diethylacrylate (868-04-2)

Guidance literature:

Reference yield: 79.0%

ethyl 2-cyano-3,3-diethylacrylate (868-04-2) + benzyl chloride (100-44-7) → ethyl 3-benzyl-2-cyano-3-ethylpentanoate

Guidance literature:

With magnesium; In diethyl ether; for 1h; Heating;

DOI:10.3891/acta.chem.scand.53-0133

upstream raw materials:

ethyl 2-cyanoacetate

pentan-3-one

Downstream raw materials:

3-Ethyl-2-cyan-pentansaeure-ethylester

3-ethyl-2-cyano-2-methyl-pent-3-enoic acid ethyl ester

3,3-Diaethyl-1,2,2-tricyan-cyclopropan-1-carbonsaeure-aethylester

4,4-diethyl-2,6-dioxo-piperidine-3,5-dicarbonitrile

Refernces

• 1、 Liu, Min Ting,Ho, Jianghai,Liu, Jason Karl,Purakait, Radhanath,Morzan, Uriel N.,Ahmed, Lucky,Batista, Victor S.,Matsunami, Hiroaki,Ryan, Kevin. "Carbon chain shape selectivity by the mouse olfactory receptor OR-I7". supporting information. p. 2541 - 2548. Retrieved 2018/04/12.
• 2、 Jenner, Gérard. "Steric effects in high pressure Knoevenagel reactions". . p. 243 - 245. Retrieved 2007/10/03.