4-Hydroxy-3,5-dimethoxybenzaldehyde azine

Base Information

• Chemical Name: 4-Hydroxy-3,5-dimethoxybenzaldehyde azine
• CAS No.: 14414-32-5
• Molecular Formula: C18H20 N2 O6
• Molecular Weight: 360.367
• Hs Code.: 2928009090
• European Community (EC) Number: 238-390-1
• DSSTox Substance ID: DTXSID20864505
• Mol file: 14414-32-5.mol

Synonyms:syringaldazine

Chemical Property of 4-Hydroxy-3,5-dimethoxybenzaldehyde azine

Chemical Property:

• Appearance/Colour: green to yellow fine crystalline powder
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 209-213 ºC
• Refractive Index: 1.5700 (estimate)
• Boiling Point: 542.5 °C at 760 mmHg
• PKA: 8.54±0.40(Predicted)
• Flash Point: 281.9 °C
• PSA: 102.10000
• Density: 1.23 g/cm³
• LogP: 2.58520
• Storage Temp.: 2-8°C
• Solubility.: DMF: slightly hazy
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 7
• Exact Mass: 360.13213636
• Heavy Atom Count: 26
• Complexity: 405

Purity/Quality:

98%,99%, ^*data from raw suppliers

Syringaldazine 99+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Hazard;Xi
• Hazard Codes: Xi,Hazard
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1O)OC)C=NN=CC2=CC(=C(C(=C2)OC)O)OC
• Uses: Syringaldazine has been used as a substrate to determine the enzymatic activity of the cuticular laccase. Syringaldazine has been used as a substrate to measure the enzymatic activity of recombinant laccase.

Technology Process of 4-Hydroxy-3,5-dimethoxybenzaldehyde azine

There total 3 articles about 4-Hydroxy-3,5-dimethoxybenzaldehyde azine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

syringic aldehyde (134-96-3) → 4,4'-hydrazine-1,2-diylidenebis(methan-1-yl-1-ylidene)bis(2,6-dimethoxyphenol) (14414-32-5)

Guidance literature:

With carbazic acid; at 60 ℃; for 3h; Neat (no solvent);

DOI:10.1021/ol202593g

Reference yield: 70.0%

N'-(4-hydroxy-3,5-dimethoxybenzylidene)-2-cyanoacetohydrazide → 4,4'-hydrazine-1,2-diylidenebis(methan-1-yl-1-ylidene)bis(2,6-dimethoxyphenol) (14414-32-5)

Guidance literature:

With hydrazine hydrate; In 1,4-dioxane; for 5h; Reflux;

DOI:10.1002/jhet.3850

Reference yield:

→ 4,4'-hydrazine-1,2-diylidenebis(methan-1-yl-1-ylidene)bis(2,6-dimethoxyphenol) (14414-32-5)

Guidance literature:

Syringaldehyd, NaOH, NH2NH2*HCl;

DOI:10.1021/ac60298a003

upstream raw materials:

syringic aldehyde

Downstream raw materials:

4-acetoxy-3,5-dimethoxybenzaldehyde

Refernces

• 1、 Bauer,Rupe. "". . p. 421. Retrieved 1971.