2,2,3,3,3-Pentafluoropropylamine

Base Information

• Chemical Name: 2,2,3,3,3-Pentafluoropropylamine
• CAS No.: 422-03-7
• Molecular Formula: C3H4F5N
• Molecular Weight: 149.063
• Hs Code.: 2921199090
• European Community (EC) Number: 207-010-6
• UNII: TD4K3W9C6K
• DSSTox Substance ID: DTXSID00195026
• Nikkaji Number: J196.087C
• Wikidata: Q72499851
• Mol file: 422-03-7.mol

Synonyms:2,2,3,3,3-Pentafluoropropylamine;422-03-7;2,2,3,3,3-pentafluoropropan-1-amine;C3H4F5N;EINECS 207-010-6;1H,1H-Perfluoropropylamine;TD4K3W9C6K;1-Propanamine, 2,2,3,3,3-pentafluoro-;2,2,3,3,3-PENTAFLUORO-1-PROPANAMINE;pentafluoropropylamine;UNII-TD4K3W9C6K;SCHEMBL26359;1H,1H-Pentafluoropropylamine;AMY7134;DTXSID00195026;C3-H4-F5-N;2,2,3,3,3-penta-fluoropropylamine;2,2,3,3,3-pentafluoro-propylamine;MFCD00042459;2,2,3,3,3-pentafluoro-propyl amine;AKOS005063466;FS-4520;3-Amino-1,1,1,2,2-pentafluoropropane;CS-0266372;FT-0609059;P2281;2,2,3,3,3-pentafluoropropylamine, AldrichCPR;EN300-862741;J-506766

Chemical Property of 2,2,3,3,3-Pentafluoropropylamine

Chemical Property:

• Vapor Pressure: 383mmHg at 25°C
• Refractive Index: 1.297
• Boiling Point: 43 °C at 760 mmHg
• PKA: 5.89±0.30(Predicted)
• Flash Point: 49-50°C
• PSA: 26.02000
• Density: 1.4
• LogP: 1.84300
• Storage Temp.: 2-8°C
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 149.02638994
• Heavy Atom Count: 9
• Complexity: 94.9

Purity/Quality:

99% ^*data from raw suppliers

2,2,3,3,3-Pentafluoropropylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,C
• Statements: 10-34
• Safety Statements: 16-26-36-45-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(F)(F)F)(F)F)N

Technology Process of 2,2,3,3,3-Pentafluoropropylamine

There total 4 articles about 2,2,3,3,3-Pentafluoropropylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2,3,3,3-pentafluoropropionamide (354-76-7) → 2,2,3,3,3-pentafluoropropyl amine (422-03-7)

Guidance literature:

With lithium aluminium tetrahydride; dibutyl ether;

DOI:10.1039/jr9530001548

Reference yield:

<1H,1H-Pentafluor-propyl>-methansulfonat (813-31-0) → 2,2,3,3,3-pentafluoropropyl amine (422-03-7)

Guidance literature:

With ammonium hydroxide; at 175 ℃; for 24h;

DOI:10.1021/jo01068a091

Reference yield:

polytetrafluoroethylene (116-14-3,82785-14-6) + hexamethylenetetramine (100-97-0) → 2,2,3,3,3-pentafluoropropyl amine (422-03-7)

Guidance literature:

With hydrogen fluoride;

DOI:10.1007/BF00848908

upstream raw materials:

2,2,3,3,3-pentafluoropropionamide

<1H,1H-Pentafluor-propyl>-methansulfonat

polytetrafluoroethylene

hexamethylenetetramine

Downstream raw materials:

N-(2,2,3,3,3-pentafluoropropyl)benzamide

2-Methyl-N-(2,2,3,3,3-pentafluoro-propyl)-malonamic acid ethyl ester