2-Chloro-1,1,2-trifluoroethyl methyl ether

Base Information

• Chemical Name: 2-Chloro-1,1,2-trifluoroethyl methyl ether
• CAS No.: 425-87-6
• Molecular Formula: C3H4 Cl F3 O
• Molecular Weight: 148.512
• Hs Code.: 2909199090
• European Community (EC) Number: 207-038-9
• UNII: 26DEB00BBW
• DSSTox Substance ID: DTXSID60962534
• Nikkaji Number: J34.758B
• Wikidata: Q27254088
• Mol file: 425-87-6.mol

Synonyms:2-Chloro-1,1,2-trifluoroethyl methyl ether;425-87-6;2-Chloro-1,1,2-trifluoro-1-methoxyethane;1-Chloro-1,2,2-trifluoro-2-methoxyethane;ETHER, 2-CHLORO-1,1,2-TRIFLUOROETHYL METHYL;BRN 1737765;Methyl 2-chloro-1,1,2-trifluoroethyl ether;EINECS 207-038-9;Ethane, 2-chloro-1,1,2-trifluoro-1-methoxy-;26DEB00BBW;2-Chloro-1,1,2-trifluoroethylmethylether;4-02-00-00494 (Beilstein Handbook Reference);1-Chloro-1,2,2-trifluoro-3-oxabutane;C3H4ClF3O;UNII-26DEB00BBW;C3-H4-Cl-F3-O;SCHEMBL3863338;KKXBMWAROXAWSZ-UHFFFAOYSA-;DTXSID60962534;MFCD00039335;AKOS006227789;AS-81311;LS-67801;1,1,2-Trifluoro-2-chloro-1-methoxyethane;CS-0332331;FT-0611675;2-Chloro-1,1,2-trifluoro-1-methoxyethane #;D89311;Q27254088

Chemical Property of 2-Chloro-1,1,2-trifluoroethyl methyl ether

Chemical Property:

• Melting Point: -92.5°C
• Refractive Index: 1.334
• Boiling Point: 55.2°Cat760mmHg
• Flash Point: °C
• PSA: 9.23000
• Density: 1.319g/cm³
• LogP: 1.76000
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 147.9902769
• Heavy Atom Count: 8
• Complexity: 76.9

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Chloro-1,1,2-trifluoroethyl Methyl Ether ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(C(F)Cl)(F)F

Technology Process of 2-Chloro-1,1,2-trifluoroethyl methyl ether

There total 5 articles about 2-Chloro-1,1,2-trifluoroethyl methyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

methanol (67-56-1) + Chlorotrifluoroethylene (79-38-9,9036-80-0) → 2-chloro-1,1,2-trifluoroethyl methyl ether (425-87-6)

Guidance literature:

With potassium hydroxide; In methanol; at 50 ℃; for 3h;

DOI:10.1007/BF00810292

Reference yield:

1,1,2-Trichloro-1,2,2-trifluoroethane (76-13-1) → 2-chloro-1,1,2-trifluoroethyl methyl ether (425-87-6)

Guidance literature:

at 125 ℃;

DOI:10.1021/ja01595a060

Reference yield:

Chlorotrifluoroethylene (79-38-9,9036-80-0) + sodium methylate (124-41-4) → 2-chloro-1,1,2-trifluoroethyl methyl ether (425-87-6)

Guidance literature:

DOI:10.1021/ja01181a526

upstream raw materials:

methanol

Chlorotrifluoroethylene

sodium methylate

1,1,2-Trichloro-1,2,2-trifluoroethane

Downstream raw materials:

2-chloro-1,1,2-trifluoroethyl chloromethyl ether

(2-chloro-1,1,2-trifluoroethyl)dichloromethylether

(2-chloro-1,1,2-trifluoroethyl)trichloromethylether

(2,2-dichloro-1,1,2-trifluoroethyl)trichloromethylether

Refernces

• 1、 Dyer,Lee. "". . p. 257. Retrieved 1966.
• 2、 Majer, V.,Uchytilova, V.,Svoboda, V.,Posta, A.. "Enthalpies of vaporization and cohesive energies of 2-chloro-1,1,2-trifluoroethyl methyl ether, 2-chloro-1,1,2-trifluoroethyl isopropyl ether, 2-chloro-1,1,2-trifluoroethyl butyl ether, and 2-chloro-1,1,2-trifluoroethyl chlorofluoromethyl ether". . p. 761 - 766. Retrieved 2007/10/02.