N-Cyclohexyl 2-aminobenzenesulfonamide

Base Information

• Chemical Name: N-Cyclohexyl 2-aminobenzenesulfonamide
• CAS No.: 77516-54-2
• Molecular Formula: C12H18 N2 O2 S
• Molecular Weight: 254.353
• Hs Code.: 2935009090
• European Community (EC) Number: 278-708-6
• DSSTox Substance ID: DTXSID80998714
• Nikkaji Number: J309.403K
• Mol file: 77516-54-2.mol

Synonyms:N-Cyclohexyl 2-aminobenzenesulfonamide;77516-54-2;2-amino-N-cyclohexylbenzenesulfonamide;EINECS 278-708-6;2-Amino-N-cyclohexylbenzenesulphonamide;SCHEMBL11228520;DTXSID80998714;CDA51654;MFCD04035383;N-Cyclohexyl2-aminobenzenesulfonamide;AKOS000146924;SB81419;BS-29577;2-Amino-N-cyclohexylbenzene-1-sulfonamide

Chemical Property of N-Cyclohexyl 2-aminobenzenesulfonamide

Chemical Property:

• Vapor Pressure: 1.37E-07mmHg at 25°C
• Boiling Point: 429.7°C at 760 mmHg
• Flash Point: 213.7°C
• PSA: 80.57000
• Density: 1.26g/cm³
• LogP: 3.93270
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 254.10889899
• Heavy Atom Count: 17
• Complexity: 331

Purity/Quality:

99% ^*data from raw suppliers

N-Cyclohexyl 2-Aminobenzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)NS(=O)(=O)C2=CC=CC=C2N

Technology Process of N-Cyclohexyl 2-aminobenzenesulfonamide

There total 2 articles about N-Cyclohexyl 2-aminobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.7%

N-cyclohexyl-2-nitrobenzenesulfonamide (77516-53-1) → 2-amino-N-cyclohexylbenzenesulfonamide (77516-54-2)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; for 12h;

Reference yield:

cyclohexylamine (108-91-8,157973-60-9) + 2-Nitrobenzenesulfonyl chloride (1694-92-4) → 2-amino-N-cyclohexylbenzenesulfonamide (77516-54-2)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 0 - 20 °C

2: hydrogen / palladium 10% on activated carbon / methanol / 12 h

With hydrogen; triethylamine; palladium 10% on activated carbon; In methanol; dichloromethane;

upstream raw materials:

cyclohexylamine

2-Nitrobenzenesulfonyl chloride

N-cyclohexyl-2-nitrobenzenesulfonamide

Refernces