NSC15155

Base Information

• Chemical Name: NSC15155
• CAS No.: 5450-75-9
• Molecular Formula: C15H17NO2S
• Molecular Weight: 275.371
• Hs Code.: 2935009090
• Mol file: 5450-75-9.mol

Synonyms:-

Chemical Property of NSC15155

Chemical Property:

• Vapor Pressure: 1.11E-07mmHg at 25°C
• Refractive Index: 1.58
• Boiling Point: 432.4 °C at 760 mmHg
• Flash Point: 215.3 °C
• PSA: 54.55000
• Density: 1.179 g/cm³
• LogP: 3.98770

Purity/Quality:

99% ^*data from raw suppliers

4-METHYL-N-PHENETHYL-BENZENESULFONAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of NSC15155

There total 58 articles about NSC15155 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

phenethylamine (64-04-0) + p-toluenesulfonyl chloride (98-59-9) → 4-methyl-N-(2-phenylethyl)benzenesulfonamide (5450-75-9)

Guidance literature:

In pyridine; at 20 ℃; for 18h;

DOI:10.1016/S0968-0896(01)00017-7

Reference yield: 99.0%

N-(2-chloro-2-phenylethyl)tosylamide (17798-13-9) → 4-methyl-N-(2-phenylethyl)benzenesulfonamide (5450-75-9)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; sodium cyanoborohydride; In tert-butyl alcohol; at 85 ℃; for 1h; Inert atmosphere;

DOI:10.1021/jo902244y

Reference yield: 97.0%

[N-(p-tolylsulfonyl)imino]phenyliodinane (55962-05-5) + triphenethylborane (1883-35-8) → 4-methyl-N-(2-phenylethyl)benzenesulfonamide (5450-75-9)

Guidance literature:

In tetrahydrofuran; for 3h; Ambient temperature;

DOI:10.1055/s-1993-25887

upstream raw materials:

phenethylamine

p-toluenesulfonyl chloride

N-p-Tosyl-N-β-phenaethylcarbaminsaeureaethylester

bromobenzene

Downstream raw materials:

1-p-Toluolsulfonyl-1-phenethyl-hydrazin

N-tosyl-2-methyl-4-phenyl-Δ²-pyrroline

2-{2-[2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-1-yl]-ethyl}-isoindole-1,3-dione

N-dodecyl-4-methylbenzenesulfonamide

Refernces

• 1、 Hajiloo Shayegan, Mojtaba,Li, Zhong-Yuan,Cui, Xin. "Ligand-Controlled Regiodivergence for Catalytic Stereoselective Semireduction of Allenamides". supporting information. . Retrieved 2021/12/02.
• 2、 Greiner, Luca C.,Inuki, Shinsuke,Arichi, Norihito,Oishi, Shinya,Suzuki, Rikito,Iwai, Tomohiro,Sawamura, Masaya,Hashmi, A. Stephen K.,Ohno, Hiroaki. "Access to Indole-Fused Benzannulated Medium-Sized Rings through a Gold(I)-Catalyzed Cascade Cyclization of Azido-Alkynes". supporting information. p. 12992 - 12997. Retrieved 2021/07/20.