2,3,5,6-Tetrafluoro-1,4-benzenedimethanamine

Base Information

• Chemical Name: 2,3,5,6-Tetrafluoro-1,4-benzenedimethanamine
• CAS No.: 89992-50-7
• Molecular Formula: C8H8F4N2
• Molecular Weight: 208.1561
• Hs Code.: 2921590090
• Mol file: 89992-50-7.mol

Synonyms:1,4-Bis(aminomethyl)-2,3,5,6-tetrafluorobenzene;(2,3,5,6-tetrafluorobenzene-1,4-diyl)dimethanamine;[4-(aminomethyl)-2,3,5,6-tetrafluorophenyl]methanamine;1,4-benzenedimethanamine, 2,3,5,6-tetrafluoro-;Tfx diamine;Tetrafluoro-p-xylylenediamine;

Chemical Property of 2,3,5,6-Tetrafluoro-1,4-benzenedimethanamine

Chemical Property:

• Appearance/Colour: white crystals
• Vapor Pressure: 0.0808mmHg at 25°C
• Refractive Index: 1.501
• Boiling Point: 226.7 °C at 760 mmHg
• Flash Point: 97.6 °C
• PSA: 52.04000
• Density: 1.423 g/cm³
• LogP: 2.56100
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

(Perfluoro-1,4-phenylene)dimethanamine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,5,6-Tetrafluoro-1,4-benzenedimethanamine

There total 1 articles about 2,3,5,6-Tetrafluoro-1,4-benzenedimethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

3,6-bis(azidomethyl)-1,2,4,5-tetrafluorobenzene → 4-aminomethyl-2,3,5,6-tetrafluoro-phenylmethanamine (89992-50-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 1h; Inert atmosphere;

DOI:10.1002/poc.3726

Reference yield: 91.0%

4-aminomethyl-2,3,5,6-tetrafluoro-phenylmethanamine (89992-50-7) + p-toluenesulfonyl chloride (98-59-9) → 1,2,4,5-tetrafluoro-3,6-bis[(tosylamino)methyl]benzene

Guidance literature:

With potassium hydroxide; In dichloromethane; water; at 20 ℃; for 24.7h; Inert atmosphere;

DOI:10.1002/poc.3726

Reference yield: 12.0%

2,6-Pyridinedicarbonyl dichloride (3739-94-4) + 4-aminomethyl-2,3,5,6-tetrafluoro-phenylmethanamine (89992-50-7) + C31H40N2O13S3*3C8H19N → C29H36N2O13S3*C30H18F8N6O4

Guidance literature:

2,6-Pyridinedicarbonyl dichloride; 4-aminomethyl-2,3,5,6-tetrafluoro-phenylmethanamine; C₃₁H₄₀N₂O₁₃S₃*3C₈H₁₉N; With triethylamine; In chloroform; for 27h;

With hydrogenchloride; acetic acid; In water; at 90 ℃; for 1h;

Refernces