Cyclooctadecanone

Base Information

• Chemical Name: Cyclooctadecanone
• CAS No.: 6907-37-5
• Molecular Formula: C18H34O
• Molecular Weight: 266.467
• Mol file: 6907-37-5.mol

Synonyms:

Chemical Property of Cyclooctadecanone

Chemical Property:

• Vapor Pressure: 1.56E-05mmHg at 25°C
• Boiling Point: 365.5°Cat760mmHg
• Flash Point: 166.9°C
• Density: 0.843g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclooctadecanone

There total 4 articles about Cyclooctadecanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

18-Iodo-octadec-1-en-3-one (101999-62-6) → octadecan-3-one (18261-92-2) + cyclooctadecanone (6907-37-5) + Octadec-1-en-3-one (96602-68-5)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; for 3h; Yield given. Yields of byproduct given; Heating;

DOI:10.1021/ja00219a034

Reference yield:

16-bromohexadecan-1-ol (59101-28-9) → cyclooctadecanone (6907-37-5)

Guidance literature:

Multi-step reaction with 5 steps

1: PCC, celite / CH₂Cl₂ / 3 h / Ambient temperature

2: tetrahydrofuran / 0.5 h / -78 °C

3: Jones reagent / acetone / 0.08 h

4: sodium iodide / butan-2-one / 3 h / Heating

5: tributyltin hydride, AIBN / benzene / 3 h / Heating

With jones reagent; 2,2'-azobis(isobutyronitrile); Celite; tri-n-butyl-tin hydride; pyridinium chlorochromate; sodium iodide; In tetrahydrofuran; dichloromethane; acetone; butanone; benzene;

DOI:10.1021/ja00219a034

Reference yield:

cyclooctadecane-1,10-dione (13747-10-9) → cyclooctadecane (296-18-4) + cyclooctadecanone (6907-37-5)

Guidance literature:

With hydrogenchloride; amalgamated zinc;

upstream raw materials:

cyclooctadecane-1,10-dione

18-Iodo-octadec-1-en-3-one

hydrogenchloride

16-bromohexadecan-1-ol

Downstream raw materials:

cyclooctadecanol

cyclooctadecane

octadecanedioic acid