Diphenyl((phenylsulfinyl)methyl)phosphine oxide

Base Information

• Chemical Name: Diphenyl((phenylsulfinyl)methyl)phosphine oxide
• CAS No.: 87762-75-2
• Molecular Formula: C₁₉H₁₅O₂PS
• Molecular Weight: 338.367
• DSSTox Substance ID: DTXSID40455212
• Nikkaji Number: J346.751A
• Mol file: 87762-75-2.mol

Synonyms:Diphenyl((phenylsulfinyl)methyl)phosphine oxide;87762-75-2;Phosphine oxide, diphenyl(phenylsulfinylmethyl)-;DTXSID40455212;Phenyl(diphenylphosphinylmethyl) sulfoxide;Diphenyl((phenylsulfinyl)methyl)phosphineoxide;[benzenesulfinylmethyl(phenyl)phosphoryl]benzene;A922659;{[(benzenesulfinyl)methyl](phenyl)phosphoroso}benzene

Chemical Property of Diphenyl((phenylsulfinyl)methyl)phosphine oxide

Chemical Property:

• PSA: 63.16000
• LogP: 4.63150
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 340.06868795
• Heavy Atom Count: 23
• Complexity: 411

Purity/Quality:

97% ^*data from raw suppliers

Diphenyl((phenylsulfinyl)methyl)phosphineoxide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)P(=O)(CS(=O)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Diphenyl((phenylsulfinyl)methyl)phosphine oxide

There total 2 articles about Diphenyl((phenylsulfinyl)methyl)phosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyldiphenylphosphine oxide (2959-74-2) → C19H15O2PS (87762-75-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) TMEDA, n-BuLi / 1) THF, RT, 15 min; 2) RT, 15 min

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine;

DOI:10.1021/jo00176a010

Reference yield:

[(Diphenyl-phosphinoyl)-phenyl-methyl]-trimethyl-silane (87762-59-2) → C19H15O2PS (87762-75-2)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1021/jo00176a010

Reference yield: 82.0%

C19H15O2PS (87762-75-2) + 2,3-dimethyl-buta-1,3-diene (513-81-5) → 2-(Diphenyl-phosphinoyl)-4,5-dimethyl-2-phenyl-3,6-dihydro-2H-thiopyran 1-oxide (87762-90-1)

Guidance literature:

In chloroform; for 168h; Ambient temperature;

DOI:10.1021/jo00176a010

upstream raw materials:

[(Diphenyl-phosphinoyl)-phenyl-methyl]-trimethyl-silane

benzyldiphenylphosphine oxide

Downstream raw materials:

n-Butyl (diphenylphosphoryl)phenylmethyl Sulfoxide

C₂₀H₁₉O₂PS

2-(Diphenyl-phosphinoyl)-4,5-dimethyl-2-phenyl-3,6-dihydro-2H-thiopyran 1-oxide

Refernces