Ethyl methyl cyclopropane-1,2-dicarboxylate

Base Information

• Chemical Name: Ethyl methyl cyclopropane-1,2-dicarboxylate
• CAS No.: 878-14-8
• Molecular Formula: C8H12O4
• NSC Number: 245494
• DSSTox Substance ID: DTXSID10955355
• Nikkaji Number: J478.690D
• Mol file: 878-14-8.mol

Synonyms:33769-98-1;NSC245494;SCHEMBL24318092;DTXSID10955355;AKOS006282030;NSC-245494;Ethyl methyl cyclopropane-1,2-dicarboxylate;1-ETHYL 2-METHYL CYCLOPROPANE-1,2-DICARBOXYLATE

Chemical Property of Ethyl methyl cyclopropane-1,2-dicarboxylate

Chemical Property:

• XLogP3: 0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 172.07355886
• Heavy Atom Count: 12
• Complexity: 199

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(=O)C1CC1C(=O)OC

Technology Process of Ethyl methyl cyclopropane-1,2-dicarboxylate

There total 1 articles about Ethyl methyl cyclopropane-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (1R,2R)-Cyclopropane-1,2-dicarboxylic acid 1-ethyl ester 2-methyl ester (878-14-8,33769-98-1,33769-99-2)

Guidance literature:

Halbestersaeurechlorid /BRN= 947314/, Methanol;

DOI:10.1246/bcsj.50.1784

Reference yield:

Aethylmethyl-1,2-cyclopropandicarboxylat (878-14-8) → 3-oxabicyclo[3.1.0]hexane-2,4-dione (5617-74-3)

Guidance literature:

With sodium hydroxide; acetic anhydride; Multistep reaction; 1.) 15 h, reflux, 2.) 0.5 h, reflux;

DOI:10.1055/s-1983-30385

Reference yield:

Aethylmethyl-1,2-cyclopropandicarboxylat (878-14-8) → cis-1,2-cyclopropanedicarboxylic acid (696-74-2,696-75-3) + trans-1,2-cyclopropanedicarboxylic acid (58616-95-8)

Guidance literature:

With potassium hydroxide; In methanol;

DOI:10.1016/S0968-0896(99)00281-3

Downstream raw materials:

3-oxabicyclo[3.1.0]hexane-2,4-dione

cis-1,2-cyclopropanedicarboxylic acid

trans-1,2-cyclopropanedicarboxylic acid

cis-cyclopropane-1,2-dicarboxylic acid diethyl ester